Association of Circulating Transfer RNA fragments with antibody response to Mycoplasma bovis in beef cattle [PDF]
BMC Veterinary Research, 2018 Background High throughput sequencing allows identification of small non-coding RNAs. Transfer RNA Fragments are a class of small non-coding RNAs, and have been identified as being involved in inhibition of gene expression.
Eduardo Casas +5 more
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The abundance of a transfer RNA-derived RNA fragment small RNA subpopulation is enriched in cauda spermatozoa [PDF]
ExRNA, 2020 AbstractThe small RNA (sRNA) landscape of mammalian spermatozoa is considerably altered as these gametic cells migrate through the segment specific microenvironments of the epididymis. More specifically, the microRNA (miRNA) species of sRNA dominates the sRNA landscape of spermatozoa of the proximal caput segment of the epididymis.
Simone J. Stanger +6 more
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Biogenesis and Function of Transfer RNA-Related Fragments (tRFs) [PDF]
Trends in Biochemical Sciences, 2016 Noncoding small RNAs arise from the various un-annotated and annotated regions of the genome. When they arise from annotated genes, the noncoding small RNAs are functionally different from the parent genes. This is a brief review of one class of noncoding small RNAs, tRNA-related fragments (tRFs), which are generated from tRNA. tRFs have been suggested
Pankaj Kumar, Canan Kuscu, Anindya Dutta
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Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases [PDF]
Genomics & Informatics, 2015 tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs made of specific tRNA cleavage. They play regulatory roles
Yu Fu +3 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2018 Ribosome-associated noncoding (ranc) RNAs are a novel class of short regulatory RNAs with functions and origins that have not been well studied. In this present study, we functionally characterized the molecular activity of Saccharomyces cerevisiae transfer RNA (tRNA)-derived fragments (tRFs) during protein biosynthesis.
Anna Mleczko +2 more
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Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. [PDF]
Proceedings of the National Academy of Sciences, 1980 A simple and rapid method for transferring RNA from agarose gels to nitrocellulose paper for blot hybridization has been developed. Poly(A)+ and ribosomal RNAs transfer efficiently to nitrocellulose paper in high salt (3 M NaCl/0.3 M trisodium citrate) after denaturation with glyoxal and 50% (vol/vol) dimethyl sulfoxide.
Patricia S. Thomas
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Mycobacterium tuberculosis Infection Drives Mitochondria-Biased Dysregulation of Host Transfer RNA–Derived Fragments [PDF]
The Journal of Infectious Diseases, 2020 Abstract Background Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, causes 10 million infections and 1.5 million deaths per year worldwide. The success of Mtb as a human pathogen is directly related to its ability to suppress host responses, which are critical for clearing ...
Monika M. Looney +3 more
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Self‐assembly of transfer RNA fragments [PDF]
FEBS Letters, 1970 A.D. Mirzabekov +3 more
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Plant transfer RNA‐derived fragments: Biogenesis and functions [PDF]
Journal of Integrative Plant Biology, 2021 AbstractProcessing of mature transfer RNAs (tRNAs) produces complex populations of tRNA‐derived fragments (tRFs). Emerging evidence shows that tRFs have important functions in bacteria, animals, and plants. Here, we review recent advances in understanding plant tRFs, focusing on their biological and cellular functions, such as regulating stress ...
Xuan Ma, Chunyan Liu, Xiaofeng Cao
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Synaptic vesicles contain small ribonucleic acids (sRNAs) including transfer RNA fragments (trfRNA) and microRNAs (miRNA). [PDF]
Sci Rep, 2015 Li H +4 more
europepmc +3 more sources