Results 51 to 60 of about 162,073 (298)

A Study of Changes in Prohepcidin and Iron Levels in Patients with Liver Transplant and Chronic Viral Hepatitis

Namık Kemal Tıp Dergisi, 2023
Aim:To study changes in hepcidin, a key protein synthesized in the liver, following chronic viral hepatitis, cirrhosis and/or liver transplant, as well as the effect of hepcidin level variation on liver function tests and iron levels.Materials and ...
Özlem ÖZDEMİR, Mesut AKARSU, Pınar TOSUN TAŞAR, Faize YÜKSEL, Aylin BACAKOĞLU, Tarkan ÜNEK, Fatih DEMİRKAN, Sedat KARADEMİR   +7 more
doaj   +1 more source

Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection

Frontiers in Immunology, 2022
Acinetobacter baumannii is a human bacterial pathogen of increasing concern in clinical settings due to the emergence of antibiotic resistant strains and the lack of effective therapeutics.
Somshukla Chaudhuri, Iraj Rasooli, Ramin Hatefi Oskouei, Mahdi Pishgahi, Abolfazl Jahangir, Vahid Farshchi Andisi, Anthony B. Schryvers   +6 more
doaj   +1 more source

Host iron binding proteins acting as niche indicators for Neisseria meningitidis

, 2009
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited - Copyright ...
Philip W Jordan, Jordan, Philip W., Philip W. Jordan, Jordan Philip W., Saunders Nigel J., Jordan, PW, Saunders, Nigel, Saunders, NJ, Nigel J Saunders, Saunders, Nigel J., Nigel J. Saunders   +10 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Iron metabolism in trypanosomatids, and its crucial role in infection. [PDF]

, 2010
Iron is almost ubiquitous in living organisms due to the utility of its redox chemistry. It is also dangerous as it can catalyse the formation of reactive free radicals - a classical double-edged sword.
Taylor, MC, Kelly, JM
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Common antigenic domains in transferrin-binding protein 2 of Neisseria meningitidis, Neisseria gonorrhoeae, and Haemophilus influenzae type b [PDF]

Infection and Immunity, 1992
There is now considerable evidence to show that in the Neisseria and Haemophilus species, membrane receptors specific for either transferrin or lactoferrin are involved in the acquisition of iron from these glycoproteins. In Neisseria meningitidis, the transferrin receptor appears to consist of two proteins, one of which (TBP 1) has an M(r) of 95,000 ...
P, Stevenson, P, Williams, E, Griffiths
openaire   +2 more sources

Proteomic and Postproteomic Characterization of Keratan Sulfate-Glycanated Isoforms of Thyroglobulin and Transferrin Uniquely Elaborated by Papillary Thyroid Carcinomas. [PDF]

, 2003
Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance.
Colombatti, Alfonso, Monica Schiappacassi, COLOMBATTI, A., Timothy Ellis, Brown, Gavin, Ellis, Timothy, Grasso, S., Perris, Roberto, Roberto Perris, Michele Bisceglia, Goletz, Steffen, Mueller, E.C., MAGRO, M., Bisceglia, Michele, Albrecht Otto, GOLETZ, S., MLLER, E. C., Gaetano Magro, PERISSINOTTO, D., Müller, Eva-Christina, Bisceglia, M., Perris, R., Otto, Albrecht, Gavin Brown, ELLIS, T., Perissinotto, Daniela, Steffen Goletz, AND PERRIS, Magro, Gaetano, Grasso, Sebastiano, Magro, G., OTTO, A., Schiappacassi, Monica, Alfonso Colombatti, BROWN, G., Eva-Christina Müller, Daniela Perissinotto, BISCEGLIE, M., Sebastiano Grasso, SCHIAPPACASSI, M.   +39 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Sprouty2 Regulates Endocytosis and Degradation of Fibroblast Growth Factor Receptor 1 in Glioblastoma Cells

Cells
The Sprouty (SPRY) proteins are evolutionary conserved modulators of receptor tyrosine kinase (RTK) signaling. SPRY2 inhibits fibroblast growth factor (FGF) signaling, whereas it enhances epidermal growth factor (EGF) signaling through inhibition of EGF ...
Barbara Hausott, Lena Pircher, Michaela Kind, Jong-Whi Park, Peter Claus, Petra Obexer, Lars Klimaschewski   +6 more
doaj   +1 more source