Results 41 to 50 of about 162,073 (298)

Effects of ultrasound therapy on the synovial fluid proteome in a rabbit surgery-induced model of knee osteoarthritis

BioMedical Engineering OnLine, 2019
Background Ultrasound (US) therapy may improve osteoarthritis symptoms. We investigated the effects of US on the synovial fluid (SF) proteome in a rabbit knee osteoarthritis (KOA) model to explore its therapeutic mechanisms.
Qinglu Luo, Shuangquan Ji, Zhimi Li, Tao Huang, Siqin Fan, Qin Xi   +5 more
doaj   +1 more source

Gonococcal Genes Encoding Transferrin-Binding Proteins A and B Are Arranged in a Bicistronic Operon but Are Subject to Differential Expression [PDF]

Infection and Immunity, 2001
ABSTRACTNeisseria gonorrhoeaeis capable of utilizing host iron-binding proteins, such as transferrin, lactoferrin, and hemoglobin, as the sole source of iron. The receptor involved in transferrin iron acquisition is composed of two distinct transferrin-binding proteins, TbpA and TbpB. The genes that encode these proteins are linked on the chromosome in
C, Ronpirin, A E, Jerse, C N, Cornelissen   +2 more
openaire   +2 more sources

Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]

, 2004
Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett, Richter, Dagmar-Ulrike, Volker Briese, Jeschke, Udo, Klaus Friese, Ioannis Mylonas, Annett Streu, Udo Jeschke, Briese, Volker, Mylonas, Ioannis, Müller, Heiner, Dagmar-Ulrike Richter, Friese, Klaus, Heiner Müller   +13 more
core   +1 more source

Delineating the regions of human transferrin involved in interactions with transferrin binding protein B from Neisseria meningitidis. [PDF]

Molecular microbiology, 2011
Pathogenic bacteria in the Neisseriaceae possess a surface receptor mediating iron acquisition from human transferrin (hTf) that consists of a transmembrane iron transporter (TbpA) and a surface-exposed lipoprotein (TbpB). In this study, we used hydrogen/deuterium exchange coupled to mass spectrometry (H/DX-MS) to elucidate the effects on hTf by ...
Jessmi M L, Ling, Collin H, Shima, David C, Schriemer, Anthony B, Schryvers   +3 more
openaire   +2 more sources

Transferrin-binding protein B isolated from Neisseria meningitidis discriminates between apo and diferric human transferrin [PDF]

Biochemical Journal, 1998
Neisseria meningitidis utilization of human serum transferrin (hTF)-bound iron is an important pathogenicity determinant. The efficiency of this system would clearly be increased through preferential binding of diferric hTF over the iron-free form. To characterize this process, functionally active meningococcal transferrin-binding protein A (TbpA) and ...
I C, Boulton, A R, Gorringe, N, Allison, A, Robinson, B, Gorinsky, C L, Joannou, R W, Evans   +6 more
openaire   +2 more sources

The amino acid selected for generating mutant TbpB antigens defective in binding transferrin can compromise the in vivo protective capacity

Scientific Reports, 2018
Haemophilus parasuis is the causative agent of the Glässer’s disease (GD), one of the most important bacterial diseases that affect young pigs worldwide.
João Antônio Guizzo, Somshukla Chaudhuri, Simone Ramos Prigol, Rong-hua Yu, Cláudia Cerutti Dazzi, Natalia Balbinott, Gabriela Paraboni Frandoloso, Luiz Carlos Kreutz, Rafael Frandoloso, Anthony Bernard Schryvers   +9 more
doaj   +1 more source

An In-Silico Investigation to Design a Multi-Epitopes Vaccine against Multi-Drug Resistant Hafnia alvei

Vaccines, 2022
Antimicrobial resistance has become a significant health issue because of the misuse of antibiotics in our daily lives, resulting in high rates of morbidity and mortality.
Fahad M. Alshabrmi, Faris Alrumaihi, Sahar Falah Alrasheedi, Wafa Abdullah I. Al-Megrin, Ahmad Almatroudi, Khaled S. Allemailem   +5 more
doaj   +1 more source

Potential Role of Transferrin and Vascular Cell Adhesion Molecule 1 in Differential Diagnosis Among Patients with Tauopathic Atypical Parkinsonian Syndromes

Diagnostics
Background/Objectives: Transferrin is a multi-task protein commonly known for binding iron; however, it is involved in multiple crucial processes, including antimicrobial activity, the growth of different cell types, differentiation, chemotaxis, the cell
Natalia Madetko-Alster, Dagmara Otto-Ślusarczyk, Marta Struga, Patryk Chunowski, Piotr Alster   +4 more
doaj   +1 more source

Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity

Molecules, 2019
The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite appealing in cancer chemotherapy.
Bruno Demoro, Andreia Bento-Oliveira, Fernanda Marques, João Costa Pessoa, Lucía Otero, Dinorah Gambino, Rodrigo F. M. de Almeida, Ana Isabel Tomaz   +7 more
doaj   +1 more source

Stabilization of the CD81 Large Extracellular Loop with De Novo Disulfide Bonds Improves Its Amenability for Peptide Grafting

Pharmaceutics, 2018
Tetraspan proteins are significantly enriched in the membranes of exosomal vesicles (EVs) and their extracellular domains are attractive targets for engineering towards specific antigen recognition units. To enhance the tolerance of a tetraspanin fold to
Stefan Vogt, Gerhard Stadlmayr, Katharina Stadlbauer, Flávio Sádio, Peter Andorfer, Johannes Grillari, Florian Rüker, Gordana Wozniak-Knopp   +7 more
doaj   +1 more source