Results 111 to 120 of about 137,943 (306)

Serum Carbohydrate Deficient Transferrin as a Sensitive Marker in Diagnosing Alcohol Abuse: A Case Control Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Teena Thomas, Jayadevan Sreedharan
doaj   +1 more source

Population genetic characteristics of two crucian carp varieties derived from distant hybridization

open access: yesReproduction and Breeding
The Hefang crucian carp (HFJ) derived from Carassius cuvieri (♀) × C. auratus red var. (♂) and the crucian carp-like homodiploid fish (NCRC) derived from Cyprinus carpio (♀) × Megalobrama amblycephala (♂) are important germplasm resources of crucian carp.
Wenjie Luo   +9 more
doaj   +1 more source

Some parameters of innate immunity in senile group patients with eye injury

open access: yesOftalʹmologiâ, 2014
Purpose: Investigation of the parameters of innate immunity in senile group patients with eye injury.Methods: Standard ophthalmologic and immunologic study of 12 patients aged 63±11 with eye injury complicated by inflamma- tion.
I. K. Namazova   +2 more
doaj   +1 more source

Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron-1

open access: yes, 2011
concentrations were: none (open bars), 50 μM (light stipled bars), 100 μM (medium stipled bars), 200 μM (dark stipled bars), and 500 μM (solid bars). . . Triplicate wells were harvested and counted after 3 days or after 7 days (with one renewal of FAC in
Donald J Messner (82604)   +1 more
core   +1 more source

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

open access: yesAdvanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul   +12 more
wiley   +1 more source

Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron-2

open access: yes, 2011
Itional 16 weeks in four separate experiments. Media additions during the promotion phase and the number of replicates were: 200 μM ammonium citrate (AmCit), n = 4 (- MNNG), n = 4 (+ MNNG); 200 μM ferric ammonium citrate (FAC), n = 3 (- MNNG), n = 4 ...
Donald J Messner (82604)   +1 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Monitoring of transferrin isoforms in biological samples by capillary electrophoresis.

open access: yes, 2017
Work dealing with the monitoring of transferrin isoforms in human serum and other body fluids by capillary electrophoresis is reviewed. It comprises capillary zone electrophoresis and capillary isoelectric focusing efforts that led to the exploration and
Jitka Caslavska   +3 more
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

open access: yesAdvanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti   +13 more
wiley   +1 more source

Transferrin receptor 2 is crucial for iron sensing in human hepatocytes

open access: yes, 2010
Hepcidin expression in vivo is regulated in proportion to iron status (i.e., increased by iron loading and decreased in iron deficiency). However, in vitro studies with hepatoma cell lines often show an inverse relationship between iron status and ...
Hughes, R.D.   +6 more
core  

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