Results 21 to 30 of about 364,066 (237)

Transferrin Saturation and Screening of Genetic Hemochromatosis [PDF]

Clinical Chemistry, 1998
Genetic hemochromatosis is the most frequent inherited disease in Caucasian populations. The gene located on the short arm of chromosome 6 was cloned in 1996 (1) and unfortunately named HLA-H. It encodes a protein that is very similar to HLA class I proteins.
M, Vernet, J Y, Le Gall
openaire   +2 more sources

Proteomic and Postproteomic Characterization of Keratan Sulfate-Glycanated Isoforms of Thyroglobulin and Transferrin Uniquely Elaborated by Papillary Thyroid Carcinomas. [PDF]

, 2003
Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance.
Goletz, Steffen, Colombatti, Alfonso, Bisceglia, Michele, Perissinotto, Daniela, Magro, Gaetano, Brown, Gavin, Grasso, Sebastiano, Müller, Eva-Christina, Ellis, Timothy, Otto, Albrecht, Perris, Roberto, Schiappacassi, Monica   +11 more
core   +5 more sources

Distribution of Transferrin Saturations in the African-American Population [PDF]

Blood, 1998
To determine if transferrin saturations in African Americans may reflect the presence of a gene that influences iron metabolism, we analyzed the distribution of these values in 808 African Americans from the second National Health and Nutrition Survey. We tested for a mixture of three normal distributions consistent with population genetics for a major
V R, Gordeuk, C E, McLaren, A C, Looker, V, Hasselblad, G M, Brittenham   +4 more
openaire   +3 more sources

Fibrillation of transferrin [PDF]

, 2012
The nature of fibrillar deposits from aqueous solutions of human serum and recombinant human transferrin on mica and carbon-coated formvar surfaces has been ...
Moreton, Ben, Costantini, Giovanni, Scrivens, James H., Sadler, P. J., Scarff, Charlotte A., Giovanni Costantini, Scrivens, James, Charlotte A. Scarff, Peter J. Sadler, Sadler, Peter J., Booyjzsen, Claire, Ben Moreton, Portman, Ian, James H. Scrivens, Claire Booyjz̈sen, Portman, Ian J., Ian Portman   +16 more
core   +1 more source

Transferrin Index: An Alternative Method for Calculating the Iron Saturation of Transferrin

Clinical Chemistry, 1992
Abstract We surveyed 140 clinical chemistry laboratories in Australia to establish which laboratory methods they used to determine serum iron status: 125 measured serum iron (Fe), 85 measured transferrin (TRF), 47 measured total iron-binding capacity (TIBC), and 14 measured both TRF and TIBC.
Beilby, J., Olynyk, J., Ching, S., Prins, A., Swanson, N., Reed, W., Harley, H., Garcia-Webb, P.   +7 more
openaire   +2 more sources

Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment

Case Reports in Gastrointestinal Medicine, 2021
Symptomatic iron overload and hyperferritinemia are rarely mentioned as complications of chronic hepatitis B infection. We report a case of a 70-year-old woman who presented with symptoms of iron overload including aches in the calves, fatigue, poor ...
Tze Tong Tey, Richard Yiu, Wei Qiang Leow   +2 more
doaj   +1 more source

The effect of systemic iron status on osteoarthritis: A mendelian randomization study

Frontiers in Genetics, 2023
Objective: To assess the causal effect of systemic iron status by using four biomarkers (serum iron; transferrin saturation; ferritin; total iron-binding capacity) on knee osteoarthritis (OA), hip OA, total knee replacement, and total hip replacement ...
Guangfeng Ruan, Yi Ying, Shilong Lu, Zhaohua Zhu, Shibo Chen, Muhui Zeng, Ming Lu, Song Xue, Jianwei Zhu, Peihua Cao, Tianyu Chen, Xiaoshuai Wang, Shengfa Li, Jia Li, Yu Liu, Yanqi Liu, Yan Zhang, Changhai Ding, Changhai Ding, Changhai Ding   +19 more
doaj   +1 more source

Predicting C282Y Homozygote Genotype for Hemochromatosis Using Serum Ferritin and Transferrin Saturation Values from 44,809 Participants of the HEIRS Study

Canadian Journal of Gastroenterology and Hepatology, 2014
INTRODUCTION: The simultaneous interpretation of serum ferritin level and transferrin saturation has been used as a clinical guide to diagnose genetic hemochromatosis.
Andrew Lim, Mark Speechley, Paul C Adams
doaj   +1 more source

Low levels of serum ferritin and moderate transferrin saturation lead to adequate hemoglobin levels in hemodialysis patients, retrospective observational study.

PLoS ONE, 2017
BackgroundOptimal iron levels in patients on hemodialysis are currently unknown, and a higher level than that for the healthy population is usually set for such patients considering the use of erythropoiesis-stimulating agents or the occurrence of ...
Chie Ogawa, Ken Tsuchiya, Naohisa Tomosugi, Fumiyoshi Kanda, Kunimi Maeda, Teiryo Maeda   +5 more
doaj   +1 more source

Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis [PDF]

, 1994
Transferrin, an iron-transporting serum glycoprotein, is efficiently taken up into cells by the process of receptor-mediated endocytosis. Transferrin receptors are found on the surface of most proliferating cells, in elevated numbers on erythroblasts and
Matt Cotten, David Curiel, Curiel, David T., Wagner, Ernst, Ernst Wagner, Cotten, Matt   +5 more
core   +1 more source