Results 41 to 50 of about 125,176 (265)

Continuous Cooling Transformation Behaviour and Bainite Transformation Kinetics of 23CrNi3Mo Carburised Steel

Metals, 2020
In this study, the phase transformation behaviour of the carburised layer and the matrix of 23CrNi3Mo steel was comparatively investigated by constructing continuous cooling transformation (CCT) diagram, determining the volume fraction of retained ...
Wenjun Song, Min Lei, Mingpan Wan, Chaowen Huang   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effect of Heating Rate on the Kinetics of Martensitic Transformation of Ni-Ti-Hf alloys using Differential Scanning Calorimetry (DSC) [PDF]

Materials Research
The transformation martensite-austenite and Kinetics in Ni-Ti-Hf shape memory alloys (SMAs) were calculated for the first time. The Johnson- Mehl – Avrami- Komogorov (JMAK) equation was used to simulate the transformation Martensite- Austenite, which ...
Glauco R. de F. Brito, Walman B. de Castro, Roniere L. Soares   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Austenite Formation Kinetics of Dual-Phase Steels: Insights from a Mixed-Control Model Under Different Heating Conditions

Modelling
A semi-analytical mixed-control model based on the Non-Partitioned Local Equilibrium (NPLE) assumption was developed to simulate the austenite phase transformation kinetics during heating and isothermal processes. The model was validated by comparing the
Huifang Lan, Xiaoying Hui, Jiangbo Du, Shuai Tang, Linxiu Du   +4 more
doaj   +1 more source

Method to Evaluate the Kinetics of Bainite Transformation in Low-Temperature Nanobainitic Steel Using Thermal Dilatation Curve Analysis

Metals, 2017
The aim of this work was to develop a method to evaluate the kinetics of bainite transformation by theoretical deduction and thermal dilatation curve analysis. A Gleeble-3500 thermomechanical simulator and dilatometer (DIL805A) were employed to study the
Yaowen Xu, Guang Xu, Xinping Mao, Gang Zhao, Siqian Bao   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Effects of acicular ferrites on crystallography and incomplete transformation of low-carbon low-alloy steel

Journal of Materials Research and Technology
In this study, we investigated the effects of acicular ferrite (AF) on the crystallographic and incomplete transformation characteristics of low-carbon low-alloy steel.
Binbin Wu, Zhiquan Wang, Chengjia Shang, Zhigang Yang, Chi Zhang, Maged Elhefnawey, Li Li   +6 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source