Results 41 to 50 of about 2,293,175 (302)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Other title: Office of Children Services Transformation initial findings report

open access: yes, 2020
"February 2020."; "Mike DeWine, Governor of Ohio; Jon Husted, Lt. Governor of Ohio."; "Ohio Governor's Children's Initiative, Children Services Transformation."; "Safe children. Stable homes.
Ohio. Children Services Transformation Advisory Council
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Transformation stasis phenomenon and overall transformation kinetics of low-carbon, Nb-bearing ferrous alloy

open access: yesJournal of Materials Research and Technology, 2020
To illuminate the overall transformation kinetics of low-carbon, Nb-bearing ferrous Alloy (Nb ferrous alloy), a novel method was proposed to investigate the overall transformation behavior on the basis of bainitic transformation stasis theory.
J.H Zhao   +5 more
doaj   +1 more source

The Evaluation of Secondary Schools in Jamaica A Value-Added Approach [PDF]

open access: yes, 2021
This policy brief summarizes the new value-added method for evaluating Jamaica’s schools, explains the composite value-added measure derived from it, and presents the findings of the first complete application of the method to the evaluation of the ...
Jamaica Education Transformation Commission
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Effects of Stress State and Microstructure on Deformation-Induced Transformation and Ageing in Medium-Manganese TRIP Steels

open access: yesMetals
This study examines the mechanical response of medium-manganese TRIP steels under different stress states, focusing on deformation-induced austenite-to-martensite transformation and ageing phenomena. Two steels with distinctly different ferrite–austenite
Javier Carreno-Saavedra   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Kinetics of the cercaria-schistosomulum transformation in vivo

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1985
Sitice most studies on the cercaria-schistosomulum transformation have been carried out in vitro, the authors used the inoculation ofcercariae into the peritoneal cavity of mice tofollow the steps involved in this progressive adaptation of cercarie to ...
A. L. Melo, L. H. Pereira
doaj   +3 more sources

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