Results 51 to 60 of about 118,415 (245)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Quantitative Assessment of the Time to End Bainitic Transformation

Metals, 2019
Low temperature bainite consists of an intimate mixture of bainitic ferrite and retained austenite, usually obtained by isothermal treatments at temperatures close to the martensite start temperature and below the bainite start temperature.
Miguel A. Santajuana, Adriana Eres-Castellanos, Victor Ruiz-Jimenez, Sebastien Allain, Guillaume Geandier, Francisca G. Caballero, Carlos Garcia-Mateo   +6 more
doaj   +1 more source

Effect of ausforming on microstructure and hardness characteristics of bainitic steel

Journal of Materials Research and Technology, 2020
Effects of process parameters of the ausforming such as temperature, strain and strain rate on the martensitic start temperature, kinetics of isothermal bainitic transformation and microstructure refinement of a low carbon carbide-free bainitic steel ...
Theerawat Kumnorkaew, Junhe Lian, Vitoon Uthaisangsuk, Wolfgang Bleck   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Incompleteness of bainite transformation in quenched and tempered steel under continuous cooling conditions

Journal of Materials Research and Technology, 2020
The austenitic transformation kinetics of quenched and tempered 22CrMnNiMo steel was investigated by dilatometric measurement at different cooling rates of 0.1∼20 K/s.
F.-C. An, S.-X. Zhao, X.-K. Xue, J.-J. Wang, G. Yuan, C.-M. Liu   +5 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Research progress of dynamic phase transformation behavior of titanium alloy under thermo-mechanical coupling process

Journal of Aeronautical Materials, 2020
Deformation and phase transformation are two major topics in the study of titanium alloy materials. Titanium alloys usually require a series of complex thermo-mechanical treatments to obtain a microstructure corresponding to service performance.
FAN Jiangkun, LAI Minjie, TANG Bin, KOU Hongchao, LI Jinshan   +4 more
doaj   +1 more source

Kinetics of phase transformations

, 2015
In this thesis, the kinetics of heterogeneous solid-state phase transformations in different prototype experimental systems are investigated with focus on the development of new strategies for kinetic modelling using mean-field kinetic models. Topics cover the interrelation between the kinetic model description and the amount of available experimental ...
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source