Results 161 to 170 of about 9,299,804 (276)

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Transforming Growth Factor-β1 Induces Concurrent Periostin and SLUG Expression in Normal Human Dermal Fibroblasts: Potential Implications for Extracellular Matrix Remodeling. [PDF]

open access: yesBiomedicines
Sputa-Grzegrzolka P   +8 more
europepmc   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

open access: yesAdvanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu   +11 more
wiley   +1 more source

Transforming Growth Factor-β1 Promoter Polymorphism in Childhood Asthma

open access: yes, 2007
Purpose: The -509C/T polymorphism of the transforming growth factor (TGF)-β1 gene has been associated with asthma and atopy. We evaluate whether TGF-β1 promoter polymorphism (-509C/T) is associated with the asthma phenotype and the development of atopy ...
김경원   +5 more
core  

Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

open access: yesAdvanced Science, EarlyView.
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu   +5 more
wiley   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

Transforming Growth Factor-β1 as a Biomarker of Malignant Behavior and PD-L1 Expression in Thymic Epithelial Tumors. [PDF]

open access: yesCancer Sci
Nakazono C   +13 more
europepmc   +1 more source

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