Results 11 to 20 of about 1,959,501 (259)

Bone remodeling at microscrew interface near extraction site in the beagle dog mandible-histologic and immunohistochemical analyses

Journal of Applied Oral Science, 2013
Extraction is often used as part of orthodontic therapy, and good control of anchorage is a key step after extraction. Although microscrews can be implanted close to the extraction site in order to achieve orthodontic support, the efficiency of bone ...
Guangxi Wei, Yun Hu, Leilei Zheng, Jinfeng Huo, Tian Tang, Feng Deng   +5 more
doaj   +1 more source

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Haematologica, 2013
Megakaryocytes release platelets into the bloodstream by elongating proplatelets. In this study, we showed that human megakaryocytes constitutively release Transforming Growth Factor β1 and express its receptors.
Stefania Badalucco, Christian Andrea Di Buduo, Rita Campanelli, Isabella Pallotta, Paolo Catarsi, Vittorio Rosti, David L. Kaplan, Giovanni Barosi, Margherita Massa, Alessandra Balduini   +9 more
doaj   +1 more source

Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts

Biomolecules, 2020
Transforming growth factor-β (TGF-β) signaling is essential in embryo development and maintaining normal homeostasis. Extensive evidence shows that TGF-β activation acts on several cell types, including epithelial cells, fibroblasts, and immune cells, to
Xueke Shi, C. Young, Hongmei Zhou, Xiao-Jing Wang   +3 more
semanticscholar   +1 more source

Transforming growth factor-β1 and TGF-β2 act synergistically in the fibrotic pathway in oral submucous fibrosis: An immunohistochemical observation

Indian Journal of Medical and Paediatric Oncology, 2015
Background and objectives: Oral Submucous Fibrosis (OSF) is a potentially malignant oral disorder which leads to fibrosis of the oral mucosa and has a high rate of malignant transformation.
Venkatesh Viswanath Kamath, Shruti Krishnamurthy, Krishnanand P Satelur, Komali Rajkumar   +3 more
doaj   +1 more source

Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium

BMC Musculoskeletal Disorders, 2019
Background Nerve growth factor (NGF) contributes to pain in knee osteoarthritis (KOA) patients. Transforming growth factor-beta (TGF-β) stimulates NGF expression in chondrocytes from KOA patients.
Shotaro Takano, Kentaro Uchida, Makoto Itakura, Dai Iwase, Jun Aikawa, Gen Inoue, Manabu Mukai, Masayuki Miyagi, Kosuke Murata, Hiroyuki Sekiguchi, Masashi Takaso   +10 more
doaj   +1 more source

miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis

Molecular Therapy: Nucleic Acids, 2018
Fibrosis is common after skeletal muscle injury, undermining tissue regeneration and function. The mechanism underlying skeletal muscle fibrosis remains unveiled.
Yaying Sun, Hui Wang, Yan Li, Shaohua Liu, Jiwu Chen, Hao Ying   +5 more
doaj   +1 more source

Transforming growth factor-β in diabetic nephropathy

The Egyptian Journal of Internal Medicine, 2013
Background Renal failure is a common and serious complication of long-standing diabetes mellitus. Diabetes is the most common cause of end-stage renal failure.
Karima Y. Ahmed, Walaa F. El-Bazz, Hend A. Mohamed, Maha M. Elkeshky   +3 more
doaj   +1 more source

Regulation of transforming growth factor-β signalling by SUMOylation and its role in fibrosis

Open Biology, 2021
Fibrosis is an abnormal healing process that only repairs the structure of an organ after injury and does not address damaged functions. The pathogenesis of fibrosis is multifactorial and highly complex; numerous signalling pathways are involved in this ...
Xinyi Wang, Ting Liu, Yifei Huang, Yifeng Dai, Hui Lin   +4 more
doaj   +1 more source

Growth factors as transforming proteins [PDF]

European Journal of Biochemistry, 1989
The growth of cells in culture is controlled by stimulatory or inhibitory factors. More than 20 different polypeptide growth factors have been structurally and functionally characterized, including cloning of their cDNAs (Table 1). The total number of polypeptide growth, factors is likely to be considerably higher, since additional factors, that have ...
C H, Heldin, B, Westermark
openaire   +2 more sources

TRANSFORMING GROWTH FACTOR 1 AT LIVER TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2015
This review summarizes the current literature devoted to the analysis of the role of transforming growth factor beta 1 (TGF-β1) at liver transplantation.
R. M. Kurabekova, O. P. Shevchenko, O. M. Tsiroulnikova   +2 more
doaj   +1 more source