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Transforming Growth Factor Beta and Prostate Cancer
2005The TGF-beta superfamily is the most versatile considering the ability of its members to regulate proliferation, growth arrest, differentiation, and apoptosis of prostatic stromal and epithelial cells as well as the formation of osteoblastic metastases.
Brian, Zhu, Natasha, Kyprianou
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Transforming Growth Factor-β Signal Transduction
Circulation Research, 1996The TGF-β superfamily of cytokines comprises an array of more than two dozen secreted peptides that have been implicated as multifunctional regulators of cell growth, differentiation, and function.1 2 Members of this family are pivotal for normal development in a variety of species, providing diffusible signals that influence pattern formation, body ...
T, Brand, M D, Schneider
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Transforming growth factor β and cancer
Cancer Treatment Reviews, 1995Udgivelsesdato: 1995 ...
Nørgaard, P +3 more
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Transforming Growth Factor-Beta Protocols
2000In Vitro Assays for Measuring TGFb Growth Stimulation and Inhibition. Measurements of Active TGFb Generated by Cultured Cells. Methods For iodination of TGFb, TGFb Receptor Crosslinking and Immunoprecipitation of TGFb-Receptor Complexes. Detection of TGFb in Body Fluids and Tissues. Analysis of TGFb-Mediated Synthesis of Extracellular Matrix Components.
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Growth regulation by transforming growth factor-β
1993The name transforming growth factor-s (TGF-s) has come to represent a family of highly homologous polypeptides with a wide range of biological activities. The first member of this gene family was identified nearly a decade ago as one of two essential factors, called TGF-α and TGF-s present in the conditioned medium of a murine sarcoma virus-transformed
B A, Arrick, R, Derynck
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The American journal of pathology, 1992
The transforming growth factor-beta (TGF beta) family in mammals includes three closely related peptides that influence proliferation and numerous physiologic processes in most mesenchymal cells. In this study, Northern blots, immunohistochemistry, TGF beta radioreceptor assays, TGF beta receptor affinity labeling and [3H] thymidine incorporation were ...
M D, Johnson +3 more
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The transforming growth factor-beta (TGF beta) family in mammals includes three closely related peptides that influence proliferation and numerous physiologic processes in most mesenchymal cells. In this study, Northern blots, immunohistochemistry, TGF beta radioreceptor assays, TGF beta receptor affinity labeling and [3H] thymidine incorporation were ...
M D, Johnson +3 more
openaire +1 more source