Results 161 to 170 of about 9,295,419 (200)

Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells

Cytokine, 2004
Transforming growth factor-beta1 (TGF-beta1) is reported to exert both pro- and anti-inflammatory effects on the chronic activation of endothelial cells (ECs) in vitro by cytokines such as tumour necrosis factor-alpha (TNF-alpha). However, the effects of TGF-beta1 on acute inflammatory responses of ECs in vitro (e.g.
Harriet, Harris, Heide, Kirschenlohr, Nicole, Szabados, James, Metcalfe   +3 more
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Tissue Localization of Transforming Growth Factor-Beta1 in Pulmonary Eosinophilic Granuloma

American journal of respiratory and critical care medicine, 1996
Abstract Pulmonary eosinophilic granuloma is characterized by infiltration of the lungs with fibronodular lesions containing specialized Langerhans' cells. In some patients, progressive pulmonary fibrosis leads to significant respiratory impairment.
S, Asakura, T V, Colby, A H, Limper
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Transforming growth factor-beta1 in heart development

Mechanisms of Development, 1992
Defined biochemical stimuli regulating neonatal ventricular myocyte (cardiomyocyte) development have not been established. Since cardiomyocytes stop proliferating during the first 3-5 days of age in the rodent, locally generated 'anti-proliferative' and/or differentiation signals can be hypothesized.
G L, Engelmann, K D, Boehm, M C, Birchenall-Roberts, F W, Ruscetti   +3 more
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Tumor necrosis factor-alpha and transforming growth factor-beta1 in chronic periapical lesions

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2000
Proinflammatory cytokines are involved in the pathogenesis of periapical lesions. The purpose of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta(1) (TGF-beta(1)) in periapical pathosis and to determine their relationship to the size of the lesions.One tooth from each ...
J, Danin, L E, Linder, G, Lundqvist, L, Andersson   +3 more
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Transforming growth factor-beta1 and lung allograft fibrosis.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1998
Transforming growth factor beta1 (TGF-beta1) is a potent immunosuppressive cytokine that promotes fibrosis by enhancing the synthesis of extracellular matrix components. The repair process following lung allograft injury is due to rejection or infection replaces lung parenchyma by fibrotic tissue, leading to pulmonary dysfunction. The role of TGF-beta1
El-Gamel, A, Awad, M, Sim, E, Hasleton, P, Egan, J, Yonan, NN A, Deiraniya, A, Hutchinson, I.   +7 more
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Regulation of transforming growth factor beta1 by nitric oxide.

Cancer research, 1999
Many tumor cells or their secreted products suppress the function of tumor-infiltrating macrophages. Tumor cells often produce abundant transforming growth factor beta1 (TGF-beta1), which in addition to other immunosuppressive actions suppresses the inducible isoform of NO synthase.
Y, Vodovotz, L, Chesler, H, Chong, S J, Kim, J T, Simpson, W, DeGraff, G W, Cox, A B, Roberts, D A, Wink, M H, Barcellos-Hoff   +9 more
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[The mechanism of transforming growth factor beta1 in myofibroblast differentiation].

Zhonghua wai ke za zhi [Chinese journal of surgery], 2008
To investigate the mechanism underlying myofibroblast differentiation induced by transforming growth factor (TGF) beta1 in obliterative bronchiolitis following lung transplantation.Heterotopic tracheal transplantation was performed in Smad3 wild-type and knock-out mice to simulate the lung transplantation in human.
Hong-xu, Liu, Si-wen, Wang, Cheng-hai, Zhao, Yang, Liu, Yu, Li, Qi-gang, Zhang, Wei, Cong, Xin-gang, Lan, Shun, Xu, Li-bo, Han, Lin, Zhang   +10 more
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Mechanism of transforming growth factor-beta1 signaling:.

Kidney international. Supplement, 2001
Mechanism of transforming growth factor-beta1 signaling: Role of the mitogen-activated protein kinase. Transforming growth factor-beta1 (TGF-beta1) regulates diverse biologic activities including cell growth, cell death or apoptosis, cell differentiation, and extracellular matrix (ECM) synthesis.
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Serum transforming growth factor-beta1 in asthmatic children

2014
Background: Transforming growth factor-beta1 is a multifunctional cytokine which has been linked to the pathogenesis of subepithelial fibrosis and airway wall remodeling in bronchial asthma. Objective: To outline the changes in serum TGF-beta1 in children with bronchial asthma in relation to severity of asthma and different treatment modalities ...
El-Sayed, Zeinab A, El-Hakim, Ihab Z, El-Kerdani, Tahani A, Ghanem, Hanan M   +3 more
openaire   +1 more source

Transforming growth factor-beta1 (TGF-beta1) in penile and prostate growth in the rat during sexual maturation.

Journal of andrology, 1998
The goal of this study was to determine whether transforming growth factor-beta1 (TGF-beta1) may contribute to the arrest of penile growth and the down-regulation of androgen receptors (AR) that occur during sexual maturation in the rat penis. For this purpose, body, penis, and prostate weights were obtained from male rats of increasing ages, and penis
J, Gelman, H, Garbán, R, Shen, C, Ng, L, Cai, J, Rajfer, N F, Gonzalez-Cadavid   +6 more
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