Results 141 to 150 of about 13,909 (174)

Transforming growth factor-beta1 and lung allograft fibrosis.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1998
Transforming growth factor beta1 (TGF-beta1) is a potent immunosuppressive cytokine that promotes fibrosis by enhancing the synthesis of extracellular matrix components. The repair process following lung allograft injury is due to rejection or infection replaces lung parenchyma by fibrotic tissue, leading to pulmonary dysfunction. The role of TGF-beta1
El-Gamel, A, Awad, M, Sim, E, Hasleton, P, Egan, J, Yonan, NN A, Deiraniya, A, Hutchinson, I.   +7 more
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Regulation of transforming growth factor beta1 by nitric oxide.

Cancer research, 1999
Many tumor cells or their secreted products suppress the function of tumor-infiltrating macrophages. Tumor cells often produce abundant transforming growth factor beta1 (TGF-beta1), which in addition to other immunosuppressive actions suppresses the inducible isoform of NO synthase.
Y, Vodovotz, L, Chesler, H, Chong, S J, Kim, J T, Simpson, W, DeGraff, G W, Cox, A B, Roberts, D A, Wink, M H, Barcellos-Hoff   +9 more
openaire   +1 more source

[The mechanism of transforming growth factor beta1 in myofibroblast differentiation].

Zhonghua wai ke za zhi [Chinese journal of surgery], 2008
To investigate the mechanism underlying myofibroblast differentiation induced by transforming growth factor (TGF) beta1 in obliterative bronchiolitis following lung transplantation.Heterotopic tracheal transplantation was performed in Smad3 wild-type and knock-out mice to simulate the lung transplantation in human.
Hong-xu, Liu, Si-wen, Wang, Cheng-hai, Zhao, Yang, Liu, Yu, Li, Qi-gang, Zhang, Wei, Cong, Xin-gang, Lan, Shun, Xu, Li-bo, Han, Lin, Zhang   +10 more
openaire   +1 more source

Mechanism of transforming growth factor-beta1 signaling:.

Kidney international. Supplement, 2001
Mechanism of transforming growth factor-beta1 signaling: Role of the mitogen-activated protein kinase. Transforming growth factor-beta1 (TGF-beta1) regulates diverse biologic activities including cell growth, cell death or apoptosis, cell differentiation, and extracellular matrix (ECM) synthesis.
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Transforming growth factor-beta1 (TGF-beta1) in penile and prostate growth in the rat during sexual maturation.

Journal of andrology, 1998
The goal of this study was to determine whether transforming growth factor-beta1 (TGF-beta1) may contribute to the arrest of penile growth and the down-regulation of androgen receptors (AR) that occur during sexual maturation in the rat penis. For this purpose, body, penis, and prostate weights were obtained from male rats of increasing ages, and penis
J, Gelman, H, Garbán, R, Shen, C, Ng, L, Cai, J, Rajfer, N F, Gonzalez-Cadavid   +6 more
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The effect of transforming growth factor beta1 (TGF-beta1) on the regenerate bone in distraction osteogenesis.

Growth factors (Chur, Switzerland), 2007
Distraction osteogenesis is a well established clinical treatment for limb length discrepancy and skeletal deformities. Transforming growth factor beta 1 (TGF-beta1) is a multifunctional peptide which controls proliferation and expression of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.
Korhan, Ozkan, Levent, Eralp, Mehmet, Kocaoglu, Bulent, Ahishali, Bilge, Bilgic, Zihni, Mutlu, Mehmet, Turker, Feyza Unlu, Ozkan, Kemal, Sahin, Melih, Guven   +9 more
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Serum transforming growth factor-beta1 in asthmatic children

2014
Background: Transforming growth factor-beta1 is a multifunctional cytokine which has been linked to the pathogenesis of subepithelial fibrosis and airway wall remodeling in bronchial asthma. Objective: To outline the changes in serum TGF-beta1 in children with bronchial asthma in relation to severity of asthma and different treatment modalities ...
El-Sayed, Zeinab A, El-Hakim, Ihab Z, El-Kerdani, Tahani A, Ghanem, Hanan M   +3 more
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[Gene expression of transforming growth factor-beta1 in osteophyte development].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2010
To investigate the gene expression and potential functions of transforming growth factor-beta1 in osteophyte development.A total of 25 specimens were obtained from individuals undergoing total knee arthroplasty due to severe primary osteoarthritis. Tissue samples were embedded in paraffin wax and made into sections.
Jun-wei, Li, Xi-sheng, Weng, Gui-xing, Qiu, Zhi-hong, Wu, Jin, Jin, Hong, Zhao, Jin, Lin   +6 more
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[Effects of transforming growth factor beta1 on dendritic cells function].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2005
To investigate the effects of transforming growth factor beta1 (TGF-beta1) on dendritic cells (DC).Murine bone marrow cells were cultured with different cytokine combinations to develop immature DC (imDC, GM-CSF only) and TGFbeta-DC (GM-CSF + TGF-beta1), and their responses to lipopolysaccharide (LPS) stimulation were observed.
Mao-fang, Lin, Hai-bo, Mou, Hong, Cen
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Transforming growth factor-beta1 expression in human acoustic neuroma.

The American journal of otology, 1999
The differing clinical behavior of acoustic neuroma (AN) may be explained by the presence of specific biological features involved in tumorigenesis and growth.Transforming growth factor (TGF) beta1 is known to participate in the regulation of peripheral nerve tumors, modulating cell proliferation and differentiation with mechanisms different from those
M R, Cardillo, R, Filipo, S, Monini, N, Aliotta, M, Barbara   +4 more
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