Results 121 to 130 of about 41,942 (251)

A bronchiolitis obliterans szindróma pathomechanizmusa = Pathomechanism of bronchiolitis obliterans syndrome [PDF]

, 2009
Tüdőtranszplantált betegek légúti infekciója során a kilégzett nitrogén monoxid (NO) szint megemelkedik. A teszt specificitása magas, szenzitivitása alacsony.
Antus, Balázs, Czebe, Krisztina, Vass, Géza   +2 more
core  

Ursolic acid inhibits epithelial-mesenchymal transition in vitro and in vivo

Pharmaceutical Biology, 2019
Context: Ursolic acid (UA; 3β-hydroxy-urs-12-en-28-oic acid), one of the pentacyclic triterpenoids found in various plants and herbs, possesses some beneficial effects under pathological conditions, including combating hepatic fibrosis.
Chang-Geng Xu, Xia-Lian Zhu, Wei Wang, Xiang-Jun Zhou   +3 more
doaj   +1 more source

Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro. [PDF]

, 2011
OBJECTIVE: The origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through ...
Jimenez, Sergio A., Li, zhaodong
core   +2 more sources

Serum transforming growth factor-beta1 in asthmatic children

Egyptian Journal of Pediatric Allergy and Immunology (The), 2014
Background: Transforming growth factor-beta1 is a multifunctional cytokine which has been linked to the pathogenesis of subepithelial fibrosis and airway wall remodeling in bronchial asthma. Objective: To outline the changes in serum TGF-beta1 in children with bronchial asthma in relation to severity of asthma and different treatment modalities ...
El-Sayed, Zeinab A, El-Hakim, Ihab Z, El-Kerdani, Tahani A, Ghanem, Hanan M   +3 more
openaire   +1 more source

Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. [PDF]

, 2015
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality.
A Diazdeleon, A Dooley, A Erol, A Freund, A Gabrielli, A Gabrielli, A Gabrielli, A MacIntyre, A Salminen, A Servettaz, A Siani, A Sturrock, A Volpe, A Volpe, A Yoshizaki, AN Lyle, AZ Debbi, B Eckes, B Laleu, CB Harley, CD Bondi, CM Arlett, CM Stein, D Gvaramia, D Muñoz-Espin, D Muñoz-Espin, D Volonte, DE Furst, DF Murrell, E Rosato, E Savas, E Sikora, E Tourkina, E Tufvesson, ER Jarman, F Boin, F Gaggini, F Galdo Del, F Galdo Del, F Jiang, F Ogawa, F Ogawa, F Ogawa, F Tarhan, G Bai, G Simonini, GL Erre, GL Erre, H Sumimoto, H Xia, I Ben-Porath, I Cucoranu, I Montorfano, J Avouac, J Campisi, J El-Benna, J Goronzy, J Varga, JA Kim, JD Lambeth, JD Morrow, JF Passos, JF Passos, JH Chen, JL Barnes, JL Cracowski, JL Cracowski, JM Deursen van, JP Coppe, K Bedard, K Shimizu, KM Holmström, L Hayflick, L Hayflick, L Hecker, L Hecker, L Serrander, LL Song, M Böhm, M Chilosi, M Collado, M Elhai, M Geiszt, M Matucci-Cerinic, M Muller, M Schieber, M Storer, MD Mayes, MP Steele, MY Armanios, N Amara, N Duerrschmidt, N Manickam, N Sampson, O Babalola, P Cipriani, P Sambo, P Sambo, P Sambo, P Shivshankar, PS Tsou, Q Chen, QM Chen, R Salama, S Altenhöfer, S Bhattacharyya, S Parrinello, S Svegliati, Sergio A. Jimenez, SJ An, SK Parapuram, Sonsoles Piera-Velazquez, SR Datla, T Aoyama, T Finkel, T Kawahara, T Kuilman, T Ohtsuka, T Tchkonia, TK Kim, TR Katsumoto, VG Gorgoulis, VI Dumit, VJ Thannickal, WK Marut, WL Shen, X Duan, XM Wang, Y Allanore, Y Allanore, YH Paik   +130 more
core   +2 more sources

Quercetin inhibits transforming growth factor β1-induced epithelial–mesenchymal transition in human retinal pigment epithelial cells via the Smad pathway

Drug Design, Development and Therapy, 2018
Wenting Cai,1,* Donghui Yu,1,* Jiaqi Fan,2 Xiuwei Liang,3 Huizi Jin,1 Chang Liu,2 Meijiang Zhu,1 Tianyi Shen,1 Ruiling Zhang,1 Weinan Hu,4 Qingquan Wei,1 Jing Yu1,5 1Department of Ophthalmology, Shanghai Tenth People’s Hospital Affiliated with ...
Cai W, Yu D, Fan J, Liang X, Jin H, Liu C, Zhu M, Shen T, Zhang R, Hu W, Wei Q, Yu J   +11 more
doaj  

Irisin Attenuates Hepatic Stellate Cell Activation and Liver Fibrosis in Bile Duct Ligation Mice Model and Improves Mitochondrial Dysfunction [PDF]

Endocrinology and Metabolism
Background Liver fibrosis is a common outcome of chronic liver disease and is primarily driven by hepatic stellate cell (HSC) activation. Irisin, a myokine released during physical exercise, is beneficial for metabolic disorders and mitochondrial ...
Thuy Linh Lai, So Young Park, Giang Nguyen, Phuc Thi Minh Pham, Seon Mee Kang, Jeana Hong, Jae-Ho Lee, Seung-Soon Im, Dae-Hee Choi, Eun-Hee Cho   +9 more
doaj   +1 more source

TGF-beta signaling proteins and the Protein Ontology [PDF]

, 2009
The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the ...
Cathy, Wu, Cecilia, Arighi, Darren, Natale, Harold, Drabkin, Hongfang, Liu, Judith, Blake, Smith, Barry, Winona, Barker   +7 more
core  

TGF-ß alterations in oral squamous cell carcinoma. Narrative review.

Journal of Oral Research, 2016
The transforming growth factor beta (TGF-ß) is a cytokine that plays crucial roles in the regulation of angiogenesis, immune response, proliferation, migration and apoptosis of cells.
Jorge Candia, Carolina Somarriva, Diego Fonseca, Fernando Parada, Jorge Briceño, Alejandra Fernández   +5 more
doaj   +1 more source

Assessment of the effects of transforming growth factor beta1 (TGF-β1)-Smad2/3 on fibrosis in rat myofascial trigger points using point shear wave elastography. [PDF]

PeerJ, 2023
Fang X, Yin Y, Lun H, Su S, Zhu S.
europepmc   +1 more source