Results 131 to 140 of about 13,909 (174)
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Transforming Growth Factor-ß1 and Prostate Cancer
Scandinavian Journal of Urology and Nephrology, 2000Transforming growth factor-beta1 (TGF-beta1) is an important regulator of the normal and malignant prostate. In the non-malignant prostate, TGF-beta1 stimulates cell differentiation, inhibits epithelial cell proliferation and induces epithelial cell death. TGF-beta1 is secreted into semen and here it is an important immunosuppressive factor.
P, Wikström, A, Bergh, J E, Damber
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Mandibular Reconstruction With Transforming Growth Factor‐β1
The Laryngoscope, 1998AbstractHypothesis: Transforming growth factor‐β1 (TGF‐β1) plus demineralized bone matrix (DBM) will reconstruct a critical mandibular defect devoid of periosteum in a canine model.Study Design: Randomized, blinded, placebo‐controlled, prospective animal pilot study.Methods: Canine critical mandibular defects devoid of periosteum were reconstructed ...
D A, Sherris +3 more
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Transforming growth factor-beta1 in hemangioma of the ovary.
Gynecologic and obstetric investigation, 1998Hemangioma of the ovary is extremely rare. We report the case of a 32-year-old woman who complained of pelvic pain due to a large right adnexal mass. On surgical exploration a 10 x 8 cm hemangioma of the ovary was resected. Expression of transforming growth factor-beta1 was studied, and the possible role of this molecule in the development of the tumor
Loverro G +5 more
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Urology, 2006
To study the potential role of pelviureteral junction obstruction (PUJO) in causing progressive renal damage in children through the renal expression of epidermal growth factor (EGF) and transforming growth factor-beta1 (TGF-beta1).The expression of EGF and TGF-beta1 was evaluated in the renal tissues of 25 children with congenital hydronephrosis by ...
Yi, Yang +3 more
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To study the potential role of pelviureteral junction obstruction (PUJO) in causing progressive renal damage in children through the renal expression of epidermal growth factor (EGF) and transforming growth factor-beta1 (TGF-beta1).The expression of EGF and TGF-beta1 was evaluated in the renal tissues of 25 children with congenital hydronephrosis by ...
Yi, Yang +3 more
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Transforming growth factor-beta1 inhibits steroidogenesis in human trophoblast cells
Molecular Human Reproduction, 2002Transforming growth factor-beta (TGF-beta) is an important regulator of placental development and function. In this study, we have investigated the effect of TGF-beta1 on steroidogenesis, as well as its sites of action in the steroidogenic pathway by using a choriocarcinoma cell line, JEG-3, and a normal trophoblast cell line (NPC).
Shuang, Luo +3 more
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Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells
Cytokine, 2004Transforming growth factor-beta1 (TGF-beta1) is reported to exert both pro- and anti-inflammatory effects on the chronic activation of endothelial cells (ECs) in vitro by cytokines such as tumour necrosis factor-alpha (TNF-alpha). However, the effects of TGF-beta1 on acute inflammatory responses of ECs in vitro (e.g.
Harriet, Harris +3 more
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European cytokine network, 2002
In TGF-beta1-knockout mice, TGF-beta1-null conceptuses die during embryonic development with a penetrance of lethality that depends on the mouse genetic background. Studies have suggested that transplacental passage of maternal TGF-beta1 could account for the rescue of some TGF-beta1-null embryos.
H, Chagraoui +3 more
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In TGF-beta1-knockout mice, TGF-beta1-null conceptuses die during embryonic development with a penetrance of lethality that depends on the mouse genetic background. Studies have suggested that transplacental passage of maternal TGF-beta1 could account for the rescue of some TGF-beta1-null embryos.
H, Chagraoui +3 more
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Tissue Localization of Transforming Growth Factor-Beta1 in Pulmonary Eosinophilic Granuloma
American journal of respiratory and critical care medicine, 1996Abstract Pulmonary eosinophilic granuloma is characterized by infiltration of the lungs with fibronodular lesions containing specialized Langerhans' cells. In some patients, progressive pulmonary fibrosis leads to significant respiratory impairment.
S, Asakura, T V, Colby, A H, Limper
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Transforming growth factor-beta1 in heart development
Mechanisms of Development, 1992Defined biochemical stimuli regulating neonatal ventricular myocyte (cardiomyocyte) development have not been established. Since cardiomyocytes stop proliferating during the first 3-5 days of age in the rodent, locally generated 'anti-proliferative' and/or differentiation signals can be hypothesized.
G L, Engelmann +3 more
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Tumor necrosis factor-alpha and transforming growth factor-beta1 in chronic periapical lesions
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2000Proinflammatory cytokines are involved in the pathogenesis of periapical lesions. The purpose of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta(1) (TGF-beta(1)) in periapical pathosis and to determine their relationship to the size of the lesions.One tooth from each ...
J, Danin +3 more
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