Results 131 to 140 of about 41,942 (251)

Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS [PDF]

open access: yes, 2007
Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K   +12 more
core  

Adeno-Associated Vector mediated gene transfer of Transforming Growth Factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism

open access: yesEuropean Cells & Materials, 2005
The objective of the present study was to investigate whether cartilage anabolism in human primary osteoarthritic chondrocytes could be improved by adeno-associated virus (AAV) vector-mediated gene transduction of transforming growth factor TGF-beta1 ...
Ulrich-Vinther M.   +4 more
doaj  

Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Angelamellisy Revelian Ndibalema,1,2 Deo Kabuye,3,4 Si Wen,1 Lulu Li,1 Xin Li,1 Qiuling Fan1 1Department of Nephrology, The First Hospital of China Medical University, Shenyang 110001, People’s Republic of China; 2Kairuki Hospital, Dar es Salaam ...
Ndibalema AR   +5 more
doaj  

Factor de crecimiento transformante beta-1: estructura, función y mecanismos de regulación en cáncer Transforming growth factor beta-1: structure, function and regulation mechanisms in cancer

open access: yesSalud Pública de México, 2001
El factor de crecimiento transformante beta-1 (TGF-beta1) es sintetizado por muchas estirpes celulares como linfocitos, macrófagos y células dendríticas, y su expresión regula de manera autócrina o parácrina la diferenciación, proliferación y el estado ...
Oscar Peralta-Zaragoza   +2 more
doaj  

Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway

open access: yesThe World Journal of Men's Health
Purpose: To examine the role and mechanism of thrombospondin-1 (TSP1) in the development of fibrosis in diabetes mellitus- induced erectile dysfunction (DMED). Materials and Methods: DMED was induced by intraperitoneal streptozotocin injection.
Mancheng Xia   +11 more
doaj   +1 more source

Transforming growth factor-β1 gene polymorphism in psoriasis vulgaris

open access: yesClinical, Cosmetic and Investigational Dermatology, 2018
Heba H El-hadidi,1 Akmal S Hassan,1 Ghada El-hanafy,1 Khalda S Amr,2 Sameh F Abdelmesih,3 Mahmoud F Abdelhamid3 1Department of Dermatology, Kasr Al-Ainy University Hospitals, Cairo University, Giza, Egypt; 2Department of Molecular Genetics, National ...
El-hadidi HH   +5 more
doaj  

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