Results 211 to 220 of about 41,942 (251)
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Mandibular Reconstruction With Transforming Growth Factor‐β1
The Laryngoscope, 1998AbstractHypothesis: Transforming growth factor‐β1 (TGF‐β1) plus demineralized bone matrix (DBM) will reconstruct a critical mandibular defect devoid of periosteum in a canine model.Study Design: Randomized, blinded, placebo‐controlled, prospective animal pilot study.Methods: Canine critical mandibular defects devoid of periosteum were reconstructed ...
D A, Sherris +3 more
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Transforming Growth Factor-ß1 and Prostate Cancer
Scandinavian Journal of Urology and Nephrology, 2000Transforming growth factor-beta1 (TGF-beta1) is an important regulator of the normal and malignant prostate. In the non-malignant prostate, TGF-beta1 stimulates cell differentiation, inhibits epithelial cell proliferation and induces epithelial cell death. TGF-beta1 is secreted into semen and here it is an important immunosuppressive factor.
P, Wikström, A, Bergh, J E, Damber
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Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells
Cytokine, 2004Transforming growth factor-beta1 (TGF-beta1) is reported to exert both pro- and anti-inflammatory effects on the chronic activation of endothelial cells (ECs) in vitro by cytokines such as tumour necrosis factor-alpha (TNF-alpha). However, the effects of TGF-beta1 on acute inflammatory responses of ECs in vitro (e.g.
Harriet, Harris +3 more
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Transforming growth factor-beta1 inhibits steroidogenesis in human trophoblast cells
Molecular Human Reproduction, 2002Transforming growth factor-beta (TGF-beta) is an important regulator of placental development and function. In this study, we have investigated the effect of TGF-beta1 on steroidogenesis, as well as its sites of action in the steroidogenic pathway by using a choriocarcinoma cell line, JEG-3, and a normal trophoblast cell line (NPC).
Shuang, Luo +3 more
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Transforming growth factor-beta1 in heart development
Mechanisms of Development, 1992Defined biochemical stimuli regulating neonatal ventricular myocyte (cardiomyocyte) development have not been established. Since cardiomyocytes stop proliferating during the first 3-5 days of age in the rodent, locally generated 'anti-proliferative' and/or differentiation signals can be hypothesized.
G L, Engelmann +3 more
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European cytokine network, 2002
In TGF-beta1-knockout mice, TGF-beta1-null conceptuses die during embryonic development with a penetrance of lethality that depends on the mouse genetic background. Studies have suggested that transplacental passage of maternal TGF-beta1 could account for the rescue of some TGF-beta1-null embryos.
H, Chagraoui +3 more
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In TGF-beta1-knockout mice, TGF-beta1-null conceptuses die during embryonic development with a penetrance of lethality that depends on the mouse genetic background. Studies have suggested that transplacental passage of maternal TGF-beta1 could account for the rescue of some TGF-beta1-null embryos.
H, Chagraoui +3 more
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Association between transforming growth factor beta1 gene polymorphisms and IgA nephropathy.
Journal of nephrology, 2004Transforming growth factor beta1 (TGF-beta1) plays an important role in the modulation of cellular growth and differentiation in a wide variety of cell types and in the production/degradation of the extracellular matrix (ECM). We investigated whether G-800A, C-509T and Leu10-->Pro polymorphisms in the TGF-beta1 gene could be involved in the development
CARTURAN S +7 more
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Transforming growth factor-beta1 in hemangioma of the ovary.
Gynecologic and obstetric investigation, 1998Hemangioma of the ovary is extremely rare. We report the case of a 32-year-old woman who complained of pelvic pain due to a large right adnexal mass. On surgical exploration a 10 x 8 cm hemangioma of the ovary was resected. Expression of transforming growth factor-beta1 was studied, and the possible role of this molecule in the development of the tumor
Loverro G +5 more
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Transforming growth factor-beta1 and lung allograft fibrosis.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1998Transforming growth factor beta1 (TGF-beta1) is a potent immunosuppressive cytokine that promotes fibrosis by enhancing the synthesis of extracellular matrix components. The repair process following lung allograft injury is due to rejection or infection replaces lung parenchyma by fibrotic tissue, leading to pulmonary dysfunction. The role of TGF-beta1
El-Gamel, A +7 more
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Increased Plasma Transforming Growth Factor‐β1 in Migraine
Headache: The Journal of Head and Face Pain, 2005Background and Objectives.—Migraine is characterized by the peripheral and central sensitization of pain perceptive neural systems, and neurogenic inflammation is a key step in the development of migraine headache. We focused on transforming growth factor‐β1 (TGF‐β1), which is a multifunctional proinflammatory cytokine.
Kumiko, Ishizaki +6 more
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