Results 221 to 230 of about 41,942 (251)
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Tumor necrosis factor-alpha and transforming growth factor-beta1 in chronic periapical lesions
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2000Proinflammatory cytokines are involved in the pathogenesis of periapical lesions. The purpose of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta(1) (TGF-beta(1)) in periapical pathosis and to determine their relationship to the size of the lesions.One tooth from each ...
J, Danin +3 more
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Transforming Growth Factor‐β1 (TGF‐β1) in dentine matrix
European Journal of Oral Sciences, 1998Transforming Growth Factor‐β (TGF‐β) and other members of this family of growth factors have been implicated in tooth development and dental tissue repair. This study aimed to investigate regulatory factors for TGF‐β1 in rabbit incisor dentine matrix and the expression of receptors for TGF‐β in dental tissues better to understand the control of its ...
A J, Smith, J B, Matthews, R C, Hall
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Mechanism of transforming growth factor-beta1 signaling:.
Kidney international. Supplement, 2001Mechanism of transforming growth factor-beta1 signaling: Role of the mitogen-activated protein kinase. Transforming growth factor-beta1 (TGF-beta1) regulates diverse biologic activities including cell growth, cell death or apoptosis, cell differentiation, and extracellular matrix (ECM) synthesis.
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Regulation of transforming growth factor beta1 by nitric oxide.
Cancer research, 1999Many tumor cells or their secreted products suppress the function of tumor-infiltrating macrophages. Tumor cells often produce abundant transforming growth factor beta1 (TGF-beta1), which in addition to other immunosuppressive actions suppresses the inducible isoform of NO synthase.
Y, Vodovotz +9 more
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Transforming growth factor-beta1 expression in human acoustic neuroma.
The American journal of otology, 1999The differing clinical behavior of acoustic neuroma (AN) may be explained by the presence of specific biological features involved in tumorigenesis and growth.Transforming growth factor (TGF) beta1 is known to participate in the regulation of peripheral nerve tumors, modulating cell proliferation and differentiation with mechanisms different from those
M R, Cardillo +4 more
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[Gene expression of transforming growth factor-beta1 in osteophyte development].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2010To investigate the gene expression and potential functions of transforming growth factor-beta1 in osteophyte development.A total of 25 specimens were obtained from individuals undergoing total knee arthroplasty due to severe primary osteoarthritis. Tissue samples were embedded in paraffin wax and made into sections.
Jun-wei, Li +6 more
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[Overexpression of transforming growth factor-beta1 in degenerative ligamentum flavum].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010To investigate the role of transforming growth factor (TGF)-beta1 in degeneration of the ligamentum flavum in the lumbar spine.The degenerative ligamentum flavum was obtained during surgery from 8 patients with lumbar spinal stenosis (mean age 58.6 years), and 8 young patients (mean age 24.2 years) with acute lumbar disc herniation were included as ...
Zhao-ming, Zhong, Jian-ting, Chen
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Journal of andrology, 1998
The goal of this study was to determine whether transforming growth factor-beta1 (TGF-beta1) may contribute to the arrest of penile growth and the down-regulation of androgen receptors (AR) that occur during sexual maturation in the rat penis. For this purpose, body, penis, and prostate weights were obtained from male rats of increasing ages, and penis
J, Gelman +6 more
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The goal of this study was to determine whether transforming growth factor-beta1 (TGF-beta1) may contribute to the arrest of penile growth and the down-regulation of androgen receptors (AR) that occur during sexual maturation in the rat penis. For this purpose, body, penis, and prostate weights were obtained from male rats of increasing ages, and penis
J, Gelman +6 more
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Die Pharmazie, 2012
Cardiac myofibroblast differentiation, characterized by expression of alpha-smooth muscle actin (alpha-SMA) and fibrillar collagens, plays a key role in the adverse myocardial remodeling. Fluorofenidone (1-(3-fluorophenyl)-5-methyl-2-(1H)-pyridone, AKF-PD) is a novel pyridone antifibrotic agent, which exerts a strong antifibrotic effect.
Ling-Xi, Chen +6 more
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Cardiac myofibroblast differentiation, characterized by expression of alpha-smooth muscle actin (alpha-SMA) and fibrillar collagens, plays a key role in the adverse myocardial remodeling. Fluorofenidone (1-(3-fluorophenyl)-5-methyl-2-(1H)-pyridone, AKF-PD) is a novel pyridone antifibrotic agent, which exerts a strong antifibrotic effect.
Ling-Xi, Chen +6 more
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