Results 31 to 40 of about 53,894 (256)

Transgenerational effects of UV-B radiation on egg size, fertilization, hatching and larval size of sea urchins Strongylocentrotus intermedius [PDF]

PeerJ, 2019
Transgenerational effects are important for phenotypic plasticity and adaptation of marine invertebrates in the changing ocean. Ultraviolet-B (UV-B) radiation is an increasing threat to marine invertebrates.
Jingyun Ding, Lingling Zhang, Jiangnan Sun, Dongtao Shi, Xiaomei Chi, Mingfang Yang, Yaqing Chang, Chong Zhao   +7 more
doaj   +2 more sources

The Promise of DNA Methylation in Understanding Multigenerational Factors in Autism Spectrum Disorders

Frontiers in Genetics, 2022
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairments in social reciprocity and communication, restrictive interests, and repetitive behaviors.
Julia S. Mouat, Julia S. Mouat, Julia S. Mouat, Julia S. Mouat, Janine M. LaSalle, Janine M. LaSalle, Janine M. LaSalle, Janine M. LaSalle   +7 more
doaj   +1 more source

Epigenetic Transgenerational Inheritance of the Effects of Obesogen Exposure

Frontiers in Endocrinology, 2021
Obesity and metabolic disorders have become a worldwide pandemic affecting millions of people. Although obesity is a multifaceted disease, there is growing evidence supporting the obesogen hypothesis, which proposes that exposure to a subset of endocrine
Nicole Mohajer, Erika M. Joloya, Jeongbin Seo, Toshi Shioda, Bruce Blumberg, Bruce Blumberg, Bruce Blumberg   +6 more
doaj   +1 more source

Maternal short stature does not predict their children's fatness indicators in a nutritional dual-burden sample of urban Mexican Maya. [PDF]

, 2014
The co-existence of very short stature due to poor chronic environment in early life and obesity is becoming a public health concern in rapidly transitioning populations with high levels of poverty.
Bogin, B, Dickinson, F, Griffiths, PL, Hobbs, M, Varela-Silva, MI, Wilson, HJ   +5 more
core   +1 more source

H3K9me3 is required for inheritance of small RNAs that target a unique subset of newly evolved genes

eLife, 2019
In Caenorhabditis elegans, RNA interference (RNAi) responses can transmit across generations via small RNAs. RNAi inheritance is associated with Histone-3-Lysine-9 tri-methylation (H3K9me3) of the targeted genes.
Itamar Lev, Hila Gingold, Oded Rechavi
doaj   +1 more source

Family patterns and suicidal and violent behavior among adolescent girls : genogram analysis [PDF]

, 2018
An increase in extreme self-destructive and aggressive behaviors in adolescents has been observed in recent years. Therapeutic effectiveness seems to depend on an adequate recognition of factors that might increase the risk of extreme destructive ...
Izydorczyk, Bernadetta, Sitnik-Warchulska, Katarzyna   +1 more
core   +1 more source

Transgenerational effects of innate immune activation in broiler breeders on growth performance and immune responsiveness

Poultry Science, 2021
: The impact of transgenerational effects on growth performance and immunity has not yet been studied extensively within the poultry husbandry sector. An important factor is the impact of the hens on the physical well-being and fitness to the environment
Michel B. Verwoolde, Jürgen van Baal, Christine A. Jansen, Elisabeth A.M. Graat, David M. Lamot, Aart Lammers, Lieske van Eck   +6 more
doaj   +1 more source

Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort [PDF]

, 2013
Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic ...
A Kerjean, A Murrell, A Soubry, AD Stein, Adelheid Soubry, Amy Murtha, AP Feinberg, Autumn Bernal, BE Levin, BR Carone, BT Heijmans, C Gemma, C Gicquel, C Hoyo, C Hoyo, Cathrine Hoyo, CC Boissonnas, DC Dolinoy, DC Dolinoy, DJ Barker, Frances Wang, G Kaati, GA Dunn, GP Ravelli, H Boerschmann, H Cui, H Cui, H Cui, J Baker, J Frystyk, JA McKay, Joanne Kurtzberg, Joellen M Schildkraut, JS Dyer, KJ Stothard, LM McCowan, M Braunschweig, M Cruz-Correa, M Ollikainen, ME Pembrey, ME Pembrey, MJ Steenman, MJ Sullivan, Q Wu, R Barres, R Figueroa-Colon, R Loomba, RA Waterland, RA Waterland, RA Waterland, Randy L Jirtle, RC Painter, RC Painter, RL Jirtle, RP Steegers-Theunissen, S Honda, S Katari, S Pathak, SA Tanumihardjo, SD McDonald, SF Ng, SK Murphy, SK Murphy, SK Murphy, SS Du Plessis, Susan K Murphy, W Chao, Z Huang, Zhiqing Huang   +68 more
core   +3 more sources

Sperm-Mediated Transgenerational Inheritance [PDF]

Frontiers in Microbiology, 2017
Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons, in the fate of the internalized nucleic acid molecules and their implication in transgenerational ...
openaire   +4 more sources

Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution

Epigenetics
The epigenome and epigenetic inheritance were not included in the original modern synthesis theory or more recent extended evolutionary synthesis of evolution.
Alexandra Korolenko, Michael K. Skinner
doaj   +1 more source