Results 21 to 30 of about 25,851 (211)

Transgenerational epigenetic inheritance [PDF]

open access: yesCurrent Biology, 2003
What is it? If you thought all heritable traits are written in the DNA sequence, think again! We have come to realize that, at some alleles, the epigenetic state of the DNA can also be inherited. This is indicated by analysis of alleles where the establishment of the epigenetic state is stochastic.
Rakyan, Vardhman, Whitelaw, Emma
openaire   +2 more sources

Transgenerational developmental programming [PDF]

open access: yesHuman Reproduction Update, 2013
The concept of developmental programming suggests that the early life environment influences offspring characteristics in later life, including the propensity to develop diseases such as the metabolic syndrome. There is now growing evidence that the effects of developmental programming may also manifest in further generations without further suboptimal
Catherine E, Aiken, Susan E, Ozanne
openaire   +2 more sources

RNA-mediated transgenerational inheritance in ciliates and plants. [PDF]

open access: yes, 2017
In the age of next-generation sequencing (NGS) and with the availability of whole sequenced genomes and epigenomes, some attention has shifted from purely sequence-based studies to those of heritable epigenetic modifications.
Nowacki, Mariusz   +3 more
core   +1 more source

Family Genealogy’s Contributions to the Philosophical Problem of Birth

open access: yesGenealogy, 2018
The central philosophical problem of birth concerns the fact that it is an event necessary for all events. As such, it is the nihilated a priori of itself—in short, it is lost in an abyss of consciousness.
Stephen B. Hatton
doaj   +1 more source

Epigenetics and transgenerational inheritance

open access: yesThe Journal of Physiology, 2023
AbstractEpigenetic modifications can alter the function of genes. The epigenetics changes are caused by environmental effects, which lead to chemical modifications of the DNA or the chromatin. The mechanisms involve the influence of small interfering siRNAs on gene silencing.
openaire   +2 more sources

Pre-reproductive stress in adolescent female rats alters maternal care and DNA methylation patterns across generations

open access: yesStress, 2023
Stress during development affects maternal behavior and offspring phenotypes. Stress in adolescence is particularly consequential on brain development and maturation, and is implicated in several psychiatric disorders.
Hiba Zaidan   +4 more
doaj   +1 more source

DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration

open access: yesEpigenetics, 2021
Alterations in environmentally sensitive epigenetic mechanisms (e.g., DNA methylation) influence axonal regeneration in the spinal cord following sharp injury.
Andy Madrid   +6 more
doaj   +1 more source

Cumulative Metabolic and Epigenetic Effects of Paternal and/or Maternal Supplementation with Arachidonic Acid across Three Consecutive Generations in Mice

open access: yesCells, 2022
Apart from the known associations between arachidonic acid (AA), weight gain, and neurological and immune function, AA exposure leads to alterations in global and gene-specific DNA methylation (DNAm) and fatty acid (FA) content in human cultured cells ...
Carmen de la Rocha   +9 more
doaj   +1 more source

Transgenerational effects of maternal sexual interactions in seed beetles

open access: yes, 2020
Mating often bears large costs to females, especially in species with high levels of sexual conflict over mating rates. Given the direct costs to females associated with multiple mating, which include reductions in lifespan and lifetime reproductive ...
Rodríguez-Expósito, Eduardo   +4 more
core   +1 more source

Rural alternatives for local development: An intercultural analysis (case study from northern Ecuador)

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2022
This study takes a historical and analytical tour of the experiences, ways of life and community knowledge oriented towards the construction of alternatives to achieve development in the communities of Cotacachi and Yunguilla, Ecuador.
Anita Krainer   +2 more
doaj   +1 more source

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