Results 1 to 10 of about 17,268 (246)

Transgenerational adaptation to hypoxia. [PDF]

Sci Adv
Epigenetic inheritance alerts naïve descendants to prepare for stresses that could still be present, whereas distant descendants return to a basal state after several generations without stress. However, organisms are frequently exposed to stresses successively across generations.
Kim K, Telger A, Sarkar G, Surya S, Rothi MH, Meers MP, Wang SY, Greer EL.   +7 more
europepmc   +3 more sources

Transgenerational Genetic Effects [PDF]

Epigenomics, 2010
Since Mendel, studies of phenotypic variation and disease risk have emphasized associations between genotype and phenotype among affected individuals in families and populations. Although this paradigm has led to important insights into the molecular basis for many traits and diseases, most of the genetic variants that control the inheritance of these ...
Joseph Nadeau
exaly   +3 more sources

Transgenerational trauma and attachment

Frontiers in Psychology
An integrative approach is presented to understand the transmission mechanisms of attachment trauma and the quality of the internal working model through manifestations of bodily symptoms concerning physical and mental health. A case of dissociative symptomatology is described in a woman whose ancestors experienced individual and collective trauma ...
Zlatomira Kostova, Vanya L. Matanova
exaly   +4 more sources

Transgenerational dynamics of gut microbiota in black soldier fly larvae (Hermetia illucens) reared on a novel substrate [PDF]

Microbiology Spectrum
Understanding the transgenerational dynamics of gut microbiota in black soldier fly larvae (BSFL) is essential for optimizing their performance on novel waste substrates in industrial settings.
Shaktheeshwari Silvaraju, Amber Lim Ching Han, Tang Yong Jen, Sandra Kittelmann, Nalini Puniamoorthy   +4 more
doaj   +2 more sources

Targeting Epigenetic Dysregulation: Antioxidants as Countermeasures Against EDC-Induced Reproductive Toxicity [PDF]

Antioxidants
Ubiquitous environmental endocrine-disrupting chemicals (EDCs), including bisphenols, phthalates, and heavy metals, pose a severe and persistent threat to mammalian reproductive health worldwide. Oxidative stress acts as the pivotal mediator which drives
Yue Feng, Dake Chen, Junjing Wu, Xianwen Peng, Shuqi Mei   +4 more
doaj   +2 more sources

Obesity and endocrine-disrupting chemicals

Endocrine Connections, 2021
Obesity is now a worldwide pandemic. The usual explanation given for the prevalence of obesity is that it results from consumption of a calorie dense diet coupled with physical inactivity.
Angelica Amorim Amato, Hailey Brit Wheeler, Bruce Blumberg   +2 more
doaj   +1 more source

Modeling early germline immunization after horizontal transfer of transposable elements reveals internal piRNA cluster heterogeneity

BMC Biology, 2023
Background A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by heterochromatic ...
Amna Asif-Laidin, Karine Casier, Zoheir Ziriat, Antoine Boivin, Elise Viodé, Valérie Delmarre, Stéphane Ronsseray, Clément Carré, Laure Teysset   +8 more
doaj   +1 more source

Transgenerational Effects of Prenatal Endocrine Disruption on Reproductive and Sociosexual Behaviors in Sprague Dawley Male and Female Rats

Toxics, 2022
Endocrine-disrupting chemicals (EDCs) lead to endocrine and neurobehavioral changes, particularly due to developmental exposures during gestation and early life.
Bailey A. Kermath, Lindsay M. Thompson, Justin R. Jefferson, Mary H. B. Ward, Andrea C. Gore   +4 more
doaj   +1 more source

Association of Prenatal Famine Exposure With Inflammatory Markers and Its Impact on Adulthood Liver Function Across Consecutive Generations

Frontiers in Nutrition, 2022
Although there has been increasing recognition that famine exposure in the fetal stage damages liver function in adulthood, this deteriorated effect could be extended to the next generation remains vague.
Shiwei Yan, Jingqi Ruan, Yu Wang, Jiaxu Xu, Changhao Sun, Yucun Niu   +5 more
doaj   +1 more source

Functional Somatic Symptoms and Emotion Regulation in Children and Adolescents

Clinical Psychology in Europe, 2022
[Background] Functional Somatic Symptoms (FSS; i.e. symptoms without sufficient organic explanation) often begin in childhood and adolescence and are common to this developmental period.
Stefanie M. Jungmann, Louisa Wagner, Marlene Klein, Aleksandra Kaurin   +3 more
doaj   +1 more source