Results 121 to 130 of about 70,182 (263)

Porcine xenotransplantation in the clinical era: converging advances and unresolved barriers on the path to clinical translation - a narrative review. [PDF]

Front Immunol
Henderson D, Knoedler L, Mathieu O, Rouas-Freiss N, Cetrulo CL, Lemaitre G, Smadja DM, Fortunel NO, Lellouch AG.   +8 more
europepmc   +1 more source

Transgenic Plants

Cold Spring Harbor Symposia on Quantitative Biology, 1985
R B, Horsch, S G, Rogers, R T, Fraley
openaire   +2 more sources

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Chromatin insulators homie and nhomie can interact with distant copies either together or separately, with distinct outcomes for enhancer-promoter interactions. [PDF]

PLoS Genet
Fujioka M, Ke W, Schedl P, Jaynes JB.
europepmc   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

Developmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

Distinct thresholds condition sense posttranscriptional gene silencing initiation and amplification. [PDF]

Plant Cell
Lacroix M, Butel N, Barrios A, Yu A, Bouteiller N, Le Masson I, Vaucheret H.   +6 more
europepmc   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Erratum: Iron biofortification and homeostasis in transgenic cassava roots expressing an algal iron assimilatory protein, FEA1.

Frontiers in Plant Science, 2013
Richard eSayre
doaj   +1 more source

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems. [PDF]

Genetics
Ward JD, Reiner DJ, Daul AL, Rougvie AE.
europepmc   +1 more source