Results 201 to 210 of about 118,253 (302)

The regulatory frameworks surrounding CRISPR‐edited papaya and their impact on international commerce

Journal of the Science of Food and Agriculture, EarlyView.
Abstract The papaya tree (Carica papaya L.), native to the Americas, is cultivated in tropical regions and holds substantial economic importance, with an estimated export volume of 365 000 t in 2023. However, diseases caused by viruses, fungi, bacteria, and nematodes can lead to severe losses.
Luíza Favaratto, Mirielson L da Silva, David S Buss, Oeber F Quadros, Raul Tapia‐Tussell, José A Ventura, Antonio Alberto R Fernandes, Patricia M B Fernandes   +7 more
wiley   +1 more source

A single component landing site for efficient transgenesis using recombination-mediated insertion. [PDF]

MicroPubl Biol
Beck AA, Nonet ML.
europepmc   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple-Gene Approach: Mutant CDK4, Cyclin D1, and TERT. [PDF]

Cell Biol Int
Bai L, Takahashi M, Kobayashi J, Eitsuka T, Matsusaka H, Ozaki T, Sugano E, Tomita H, Xu Y, Kawamura K, Nakagawa K, Kiyono T, Fukuda T.   +12 more
europepmc   +1 more source

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

Movement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes, Adriana Marcelo, Ana Teresa Rajado, Rafael G. Costa, Ricardo Afonso‐Reis, Cristiana R. Madeira, Inês T. Afonso, David V.C. Brito, Adriana A. Vaz, Clévio Nóbrega   +9 more
wiley   +1 more source

Dual-cytokine-armed oncolytic HSV for enhanced tumor immunotherapy. [PDF]

Mol Ther Oncol
Dhital R, Pereira MSF.
europepmc   +1 more source

Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya, Nanna Møller Jensen, Dennis W. Dickson, Poul Henning Jensen   +3 more
wiley   +1 more source

Transgenic barley over-expressing <i>Aspergillus niger</i> phytase phyA in field trials. [PDF]

GM Crops Food
Vlčko T, Psota V, Koprna R, Harwood W, Ohnoutková L.   +4 more
europepmc   +1 more source

Identification and evaluation of novel intergenic sites in the vaccinia virus genome for transgene insertion. [PDF]

Mol Ther Oncol
Bueno-Merino C, Del Canizo A, Conesa M, Barcia M, Sallent I, Manils J, Forcales SV, Soler C, Rojas JJ.   +8 more
europepmc   +1 more source

Maternal inheritance suppresses CAA and amyloid plaques in 5xFAD (Tg7031)/APOE4 mice. [PDF]

Neuron
Saadi F, Katritch IV, Parhizkar S, Lugo B, Cho Y, Ulrich JD, Holtzman DM.   +6 more
europepmc   +1 more source