Results 191 to 200 of about 70,182 (263)

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Transposons as Tools for Future Genome Engineering in Yeasts and Filamentous Fungi

Yeast, EarlyView.
Applications of transposon‐based tools for genome engineering in fungi include transposon‐mediated mutagenesis and targeted genomic integration. ABSTRACT Transposons are fundamental genetic elements that have profoundly shaped the architecture of eukaryotic genomes.
Bingyin Peng, Masahiro Tominaga, Chengqiang Wang, Robert E. Speight, Jun Ishii   +4 more
wiley   +1 more source

Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation. [PDF]

Sci Adv
Mazzetti D, Nowicki MO, Soni H, Bernstock JD, Groff M, Esposito L, Hernandez DA, Altucci L, Krichevsky A, Fell G, Chiocca EA, Nakashima H, Mineo M, Peruzzi P.   +13 more
europepmc   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Keeping neurons in shape with fats: an educational primer for use with "Phospholipid biogenesis maintains neuronal integrity during aging and axon regeneration". [PDF]

Genetics
Lee RJ, Vaughen JP.
europepmc   +1 more source

Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis

Integrative Zoology, EarlyView.
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao, Zhaowei Zhong, Lisheng Wu, Quanyin Liu, Shaoxiong Ding   +4 more
wiley   +1 more source

A rapid and dynamic role for FMRP in the plasticity of adult neurons. [PDF]

Nat Commun
Gundermann DG, Lymer S, Lennon J, Blau J.   +3 more
europepmc   +1 more source

Harnessing oncogenic signaling to enhance oncolytic virotherapy: Lessons from EPAC-encoding vaccinia virus. [PDF]

Mol Ther Oncol
Boulton S, Singh S, Bell JC.
europepmc   +1 more source

The genome takes the wheel: CAR T with built-in circuits. [PDF]

Immunooncol Technol
Yap KM, Darcy PK, Beavis PA, Chen AXY.
europepmc   +1 more source

A single component landing site for efficient transgenesis using recombination-mediated insertion. [PDF]

MicroPubl Biol
Beck AA, Nonet ML.
europepmc   +1 more source