Results 171 to 180 of about 118,253 (302)

Specific pathogen free ten gene-edited donor pigs for xenotransplantation. [PDF]

Protein Cell
Xu K, Zhao H, Jia B, Wang J, Siddig NAMA, Jamal MA, Mao A, Liu K, Cheng W, Yang C, Wei T, Zhu F, Huo X, Jiao D, Guo J, Zhao H, Cheng W, Zhang Y, Zhang X, Jiang L, Zhang Z, Zhang W, Liang T, Zhao HY, Sun BC, Wei HJ.   +25 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Double defense: enhancing tobacco with cyanobacterial and thaumatin genes. [PDF]

Front Bioeng Biotechnol
Kyrpa T, Prokhorova Y, Kharkhota M, Kuchuk M.   +3 more
europepmc   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Promoter competition and Polycomb response elements govern transvection efficiency between co-regulated engrailed and invected genes in Drosophila. [PDF]

Genetics
Cheng Y, Perkins AT, Chan FW, Gehred ND, Bateman JR, Kassis JA.   +5 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Transcription-dependent and -independent functions of Drosophila p53 isoforms in the induction of apoptosis and senescence-associated tumorigenesis. [PDF]

Cell Death Dis
Pérez-Aguilera M, Ruiz-Losada M, Gil Cortes P, Benchaib M, Rubio C, Baena-López LA, Baonza A, Estella C.   +7 more
europepmc   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Polycomb repression works without Siesta, the <i>Drosophila</i> ortholog of mammalian PCGF3. [PDF]

Sci Adv
Kahn TG, Garrido A, Yushkova A, Kim M, Glotov A, Sreekumar S, Larsson J, Schwartz YB.   +7 more
europepmc   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

Developmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source