Results 161 to 170 of about 80,448 (304)

A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation

Food Chemistry International, EarlyView.
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee, Tien‐Fen Kuo, Chun‐Yen Yang, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Modification of internal RNA domains from the long non-coding RNA XIST refines roles in silencing and heterochromatin recruitment. [PDF]

Hum Mol Genet
Navarro-Cobos MJ, Posynick BJ, Yang C, Brown CJ.   +3 more
europepmc   +1 more source

Low‐Concentration Dopamine Potentiates Gastric Motility Through Activation of Dopamine D5 Receptor on Enteric Cholinergic Neurons

Gut Medicine, EarlyView.
ABSTRACT Background Dopamine (DA) exerts complex concentration‐dependent effects on gastrointestinal motility. Although its inhibitory action through D2‐like receptors is well‐established, the mechanisms underlying its excitatory effects remain elusive.
Xiao‐Li Zhang, Tuo Ji, Yue Zhang, Cai‐Feng Zhang, Yun‐Jing Bai, Jin Song   +5 more
wiley   +1 more source

Inducing fixation of transgenic alleles in open-pollinated populations. [PDF]

Transgenic Res
Conner AJ, Jacobs JME.
europepmc   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

The microcephaly protein Abnormal Spindle has an essential role in symmetrically dividing neural precursors to promote brain growth and development. [PDF]

Dev Biol
Chakraborty S, Florez S, Govaerts J, Hawke A, Schoborg T.   +4 more
europepmc   +1 more source

Transgenic harvest [PDF]

Nature, 2010
openaire   +2 more sources

Chromatin insulators homie and nhomie can interact with distant copies either together or separately, with distinct outcomes for enhancer-promoter interactions. [PDF]

PLoS Genet
Fujioka M, Ke W, Schedl P, Jaynes JB.
europepmc   +1 more source

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems. [PDF]

Genetics
Ward JD, Reiner DJ, Daul AL, Rougvie AE.
europepmc   +1 more source

Position effect variegation and imprinting of transgenes in lymphocytes

, 2008
Sequences proximal to transgene integration sites are able to deregulate transgene expression result-ing in complex position effect phenotypes. In addition, transgenes integrated as repeated arrays are susceptible to repeat-induced gene silencing.
Nicola Harker, Kathleen Roderick, Henrique Veiga-fern, Dimitris Kioussis, Adam Williams, Trisha Norton, Mauro Tolaini, Eleni Ktistaki, Keith Williams   +8 more
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