Signal Peptide Engineering and Codon Optimization to Enhance α-Gal A Activity for rAAV Gene Therapy of Fabry Disease. [PDF]
He S +15 more
europepmc +1 more source
Novel plant breeding techniques. Consequences of new genetic modification-based plant breeding techniques in comparison to conventional plant breeding [PDF]
Schaart, J.G., Visser, R.G.F.
core +1 more source
Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz +7 more
wiley +1 more source
Reduced Cas9 transgene silencing by incorporation of intron sequences. [PDF]
Arana S +13 more
europepmc +1 more source
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi +12 more
wiley +1 more source
Correction: The circadian genes are required in DAL neurons for <i>Drosophila</i> long-term memory formation. [PDF]
Yin JCP +5 more
europepmc +1 more source
GS2.2 G255D mutation conferred enzyme‐level glufosinate insensitivity but no whole‐plant resistance, showing trade‐offs between catalytic function and herbicide binding and providing a baseline for future studies on target‐site glufosinate resistance.
Aimone Porri +8 more
wiley +1 more source
Generation and maintenance of apical rib-like actin fibers in epithelial support cells of the Drosophila eye. [PDF]
Bhattarai A +7 more
europepmc +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Transgene-Killer-CRISPR version 2 (TKC2) eliminates occasional transgene escape by coupling with a RUBY reporter. [PDF]
Zhu M +13 more
europepmc +1 more source

