Results 21 to 30 of about 332,647 (335)

F-Box Family Genes, LTSF1 and LTSF2, Regulate Low-Temperature Stress Tolerance in Pepper (Capsicum chinense)

Plants, 2020
The F-box proteins belong to a family of regulatory proteins that play key roles in the proteasomal degradation of other proteins. Plant F-box proteins are functionally diverse, and the precise roles of many such proteins in growth and development are ...
Jelli Venkatesh, Min-Young Kang, Li Liu, Jin-Kyung Kwon, Byoung-Cheorl Kang   +4 more
doaj   +1 more source

Genetic Transformation of Artemisia carvifolia Buch with rol Genes Enhances Artemisinin Accumulation. [PDF]

PLoS ONE, 2015
The potent antimalarial drug artemisinin has a high cost, since its only viable source to date is Artemisia annua (0.01-0.8% DW). There is therefore an urgent need to design new strategies to increase its production or to find alternative sources. In the
Erum Dilshad, Rosa Maria Cusido, Karla Ramirez Estrada, Mercedes Bonfill, Bushra Mirza   +4 more
doaj   +1 more source

Improved shoot regeneration, salinity tolerance and reduced fungal susceptibility in transgenic tobacco constitutively expressing PR-10a gene

Frontiers in Plant Science, 2016
Plants in ecosystems are simultaneously exposed to abiotic and biotic stresses, which restrict plant growth and development. The complex responses to these stresses are largely regulated by plant hormones, which in turn, orchestrate the different ...
Parinita eAgarwal, Mitali eDabi, Prashant eMore, Khantika ePatel, Kalyanashis eJana, Pradeep K Agarwal   +5 more
doaj   +1 more source

Genetic modelling of PIM proteins in cancer: proviral tagging, cooperation with oncogenes, tumor suppressor genes and carcinogens.

Frontiers in Oncology, 2014
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney murine leukemia virus infection, are a family of highly homologous serine/threonine kinases that have been reported to be overexpressed in hematological malignancies
Enara eAguirre, Oliver eRenner, Maja eNarlik-Grassow, Carmen eBlanco Aparicio   +3 more
doaj   +1 more source

Functional Analysis of Polyprenyl Diphosphate Synthase Genes Involved in Plastoquinone and Ubiquinone Biosynthesis in Salvia miltiorrhiza

Frontiers in Plant Science, 2019
Polyprenyl diphosphate synthase (PPS) plays important roles in the biosynthesis of functionally important plastoquinone (PQ) and ubiquinone (UQ). However, only few plant PPS genes have been functionally characterized.
Miaomiao Liu, Yimian Ma, Qing Du, Qing Du, Xuemin Hou, Meizhen Wang, Shanfa Lu   +6 more
doaj   +1 more source

Relationship between Expression Levels and Atherogenesis in Scavenger Receptor Class B, Type I Transgenics*

Journal of Biological Chemistry, 2000
Both in vitro and in vivostudies of scavenger receptor class B type I (SR-BI) have implicated it as a likely participant in the metabolism of HDL cholesterol.
Y. Ueda, E. Gong, L. Royer, P. Cooper, O. Francone, E. Rubin   +5 more
semanticscholar   +1 more source

Developmental dopamine loss rewires striatal circuits to promote locomotion

Molecular Neurodegeneration
Background Motor symptoms of Parkinson’s disease (PD) primarily result from the degeneration of nigrostriatal dopaminergic neurons (DANs), particularly the Aldehyde Dehydrogenase 1A1-positive (ALDH1A1⁺) subpopulation.
Jie Dong, Breanna T. Sullivan, Victor M. Martinez Smith, Lupeng Wang, Lulu Tian, Justin Kung, Bin Song, Shirong Lin, Andreanna Le, Lixin Sun, Lisa Chang, Jinhui Ding, Weidong Le, Jun Jia, Huaibin Cai   +14 more
doaj   +1 more source

An approach for exploring interaction between two proteins in vivo

Frontiers in Physiology, 2014
We describe a strategy for exploring the function of protein-protein interactions in striated muscle in vivo. We describe our experience using this strategy to study the interaction of UNC-112 (kindlin) with PAT-4 (integrin linked kinase).
Hiroshi eQadota, Guy M Benian
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Mining the Utricularia gibba genome for insulator-like elements for genetic engineering

Frontiers in Plant Science, 2023
IntroductionGene expression is often controlled via cis-regulatory elements (CREs) that modulate the production of transcripts. For multi-gene genetic engineering and synthetic biology, precise control of transcription is crucial, both to insulate the ...
Daniel Laspisa, Eudald Illa-Berenguer, Sohyun Bang, Robert J. Schmitz, Wayne Parrott, Wayne Parrott, Jason Wallace, Jason Wallace, Jason Wallace   +8 more
doaj   +1 more source