Results 21 to 30 of about 24,604,955 (198)

Transglutaminase 2 Up-Regulation Is Associated with Inflammatory Response in PBMC from Healthy Subjects with Hypovitaminosis D

Medical Sciences, 2018
Recent evidence indicated that transglutaminase 2 (TG2) is involved in the adaptive immune response. Peripheral blood mononuclear cells (PBMC) have largely been used to characterize molecular mechanisms occurring in the activation of immune response ...
Daniela Caccamo, Nadia Ferlazzo, Monica Currò, Sergio Ricca, Riccardo Ientile   +4 more
doaj   +1 more source

Calcium‐dependent activation of transglutaminase 2 by nanosecond pulsed electric fields

FEBS Open Bio, 2017
Exposure of cultured human cells to nanosecond pulsed electric fields (nsPEFs) elicits various cellular events, including Ca2+ influx and cell death. Recently, nsPEFs have been regarded as a novel physical treatment useful for biology and medicine, but ...
Keiko Morotomi‐Yano, Ken‐ichi Yano
doaj   +1 more source

Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase [PDF]

, 2011
Background Plasmodium falciparum sporozoites injected by mosquitoes into the blood rapidly enter liver hepatocytes and undergo pre-erythrocytic developmental schizogony forming tens of thousands of merozoites per hepatocyte.
Piacentini Mauro, Rodolfo, Carlo, Giuseppina Di Giacomo, Doerig Christian, Di Giacomo, Giuseppina, Piacentini, Mauro, Lanar David E, William S Nicoll, Di Giacomo, G, Nicoll, W.S., Doerig, C., Hollingdale, M.R., David E Lanar, Sacci, JB, Sacci, John, John B Sacci, Piacentini, M, Zoe JM Holland, Michael R Hollingdale, Rodolfo, C., Lanar, D.E., Nicoll William S, Mauro Piacentini, Sacci John B, Doerig, Christian, Lanar, DE, Sacci, J.B., Hollingdale Michael R, Rodolfo Carlo, Hollingdale, MR, Rodolfo, C, Holland, Zoe, Lanar, David, Christian Doerig, Holland Zoe JM, Holland, Z.J.M., Carlo Rodolfo, Di Giacomo Giuseppina, Holland, ZJ, Nicoll, William, Nicoll, WS, Doerig, C, Hollingdale, Michael   +42 more
core   +1 more source

Inhibition of Transglutaminase 2 but Not of MDM2 Has a Significant Therapeutic Effect on Renal Cell Carcinoma

Cells, 2020
More than 50% of human cancers harbor TP53 mutations and increased expression of Mouse double minute 2 homolog (MDM2), which contribute to cancer progression and drug resistance. Renal cell carcinoma (RCC) has an unusually high incidence of wild-type p53,
Joon Hee Kang, Seon-Hyeong Lee, Jae-Seon Lee, Su-Jin Oh, Ji Sun Ha, Hyun-Jung Choi, Soo-Youl Kim   +6 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The over-expression of the plastidial transglutaminase from maize in Arabidopsis increases the activation threshold of photoprotection

Frontiers in Plant Science, 2016
Plastidial transglutaminase is one of the most promising enzymes in chloroplast bioenergetics due to its link with polyamine pathways and the cross talk with signals such as Ca+2 and GTP.
Nikolaos E Ioannidis, Dimitris eMalliarakis, Josep M. eTorne, Mireya eSantos, Kiriakos eKotzabasis   +4 more
doaj   +1 more source

Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes [PDF]

, 2016
Transglutaminase (TGase) catalyzes protein cross-linking reactions essential for several biological processes. In differentiating keratinocytes, TG1 (keratinocyte-type) is crucial for the cross-linking of substrate proteins required for the complete ...
Yamane, Miki, Sugimura, Kayoko, Tatsukawa, Hideki, Hitomi, Kiyotaka, Kawasaki, Hiroko   +4 more
core   +1 more source

Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype - implications for the role of transglutaminase in coeliac disease

BMC Immunology, 2012
Dendritic cells (DCs) are part of the innate immune system with a key role in initiating and modulating T cell mediated immune responses. Coeliac disease is caused by inappropriate activation of such a response leading to small intestinal inflammation ...
Dalleywater William J, Chau David YS, Ghaemmaghami Amir M   +2 more
doaj   +1 more source

Calmodulin regulates transglutaminase 2 cross-linking of Huntingtin [PDF]

, 2004
This is the publisher's version, also available electronically from "www.jneurosci.org".Striatal and cortical intranuclear inclusions and cytoplasmic aggregates of mutant huntingtin are prominent neuropathological hallmarks of Huntington's disease (HD ...
Ross, Christopher A., Troncoso, Juan C., Fitzgerald, John K., Zainelli, Gina M., Muma, Nancy A.   +4 more
core   +1 more source

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Advanced Science, 2023
Osteoblasts play an important role in the regulation of bone homeostasis throughout life. Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the urgent need for novel pharmacological targets.
Zhuo Yang, Xiao‐Wen Zhang, Fang‐Fang Zhuo, Ting‐Ting Liu, Qian‐Wei Luo, Yong‐Zhe Zheng, Ling Li, Heng Yang, Yi‐Chi Zhang, Yan‐Hang Wang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng   +12 more
doaj   +1 more source