Results 21 to 30 of about 23,528 (188)

Activation and inhibition of transglutaminase 2 in mice. [PDF]

PLoS ONE, 2012
Transglutaminase 2 (TG2) is an allosterically regulated enzyme with transamidating, deamidating and cell signaling activities. It is thought to catalyze sequence-specific deamidation of dietary gluten peptides in the small intestines of celiac disease ...
Laila Dafik, Megan Albertelli, Jorunn Stamnaes, Ludvig M Sollid, Chaitan Khosla   +4 more
doaj   +1 more source

The over-expression of the plastidial transglutaminase from maize in Arabidopsis increases the activation threshold of photoprotection

Frontiers in Plant Science, 2016
Plastidial transglutaminase is one of the most promising enzymes in chloroplast bioenergetics due to its link with polyamine pathways and the cross talk with signals such as Ca+2 and GTP.
Nikolaos E Ioannidis, Dimitris eMalliarakis, Josep M. eTorne, Mireya eSantos, Kiriakos eKotzabasis   +4 more
doaj   +1 more source

Separate Gut Plasma Cell Populations Produce Auto‐Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

Advanced Science, 2023
Dermatitis herpetiformis (DH) is an inflammatory skin disorder often considered as an extra intestinal manifestation of celiac disease (CeD).
Saykat Das, Jorunn Stamnaes, Esko Kemppainen, Kaisa Hervonen, Knut E. A. Lundin, Naveen Parmar, Frode L. Jahnsen, Jørgen Jahnsen, Katri Lindfors, Teea Salmi, Rasmus Iversen, Ludvig M. Sollid   +11 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Evaluation of Process Conditions for Ultrasonic Spray Freeze Drying of Transglutaminase

Food Technology and Biotechnology, 2020
In this study, a commercial transglutaminase enzyme was dried using an ultrasonic spray freeze drying method and the effects of the process conditions were optimized to maximize the final transglutaminase activity.
Hilal Isleroglu, Izzet Turker
doaj   +1 more source

Biological Functionalities of Transglutaminase 2 and the Possibility of Its Compensation by Other Members of the Transglutaminase Family

The Scientific World Journal, 2014
Transglutaminase 2 (TG2) is the most widely distributed and most abundantly expressed member of the transglutaminase family of enzymes, a group of intracellular and extracellular proteins that catalyze the Ca2+-dependent posttranslational modification of
Benedict Onyekachi Odii, Peter Coussons
doaj   +1 more source

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Advanced Science, 2023
Osteoblasts play an important role in the regulation of bone homeostasis throughout life. Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the urgent need for novel pharmacological targets.
Zhuo Yang, Xiao‐Wen Zhang, Fang‐Fang Zhuo, Ting‐Ting Liu, Qian‐Wei Luo, Yong‐Zhe Zheng, Ling Li, Heng Yang, Yi‐Chi Zhang, Yan‐Hang Wang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng   +12 more
doaj   +1 more source

Increased Transglutaminase 2 Expression and Activity in Rodent Models of Obesity/Metabolic Syndrome and Aging

Frontiers in Physiology, 2020
Diastolic dysfunction of the heart and decreased compliance of the vasculature and lungs (i.e., increased organ tissue stiffness) are known features of obesity and the metabolic syndrome. Similarly, cardiac diastolic dysfunction is associated with aging.
Krishna C. Penumatsa, Ines Falcão-Pires, Sara Leite, Adelino Leite-Moreira, Chinmayee D. Bhedi, Sabina Nasirova, Jing Ma, Jing Ma, Roy L. Sutliff, Roy L. Sutliff, Barry L. Fanburg   +10 more
doaj   +1 more source

Analysis of the Impact of Reformulation of the Recipe Composition on the Quality of Instant Noodles

Applied Sciences
This study aimed to evaluate how adding whey protein and transglutaminase impacts the quality of fried instant noodles. This research focused on analyzing various quality characteristics of the noodles based on the type and quantity of additives used. In
Katarzyna Marciniak-Lukasiak, Ewelina Durajczyk, Aleksandra Lukasiak, Katarzyna Zbikowska, Piotr Lukasiak, Anna Zbikowska   +5 more
doaj   +1 more source

The effect of transglutaminase-2 inhibitor on pulmonary vascular remodeling in rats with pulmonary arterial hypertension

Clinical and Experimental Hypertension, 2022
To investigate the relationship between transglutaminase type 2 (TG2) and pulmonary vascular remodeling in the formation of pulmonary arterial hypertension (PAH), and to investigate the effect of the inhibitor cystamine dihydrochloride on pulmonary ...
Ting Wang, Yan Duan, Dong Liu, Gang Li, Bin Liu   +4 more
doaj   +1 more source