Results 81 to 90 of about 1,613,986 (294)

Ultrafast Excited State Dynamics of a Verdazyl Diradical System

Photochem
While the photophysics of closed-shell organic molecules is well established, much less is known about open-shell systems containing interacting radical pairs.
Caitlyn Clark, Filip Pawłowski, David J. R. Brook, Christopher Grieco   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Time-Resolved Spectroscopic Study of N,N-Di(4-bromo)nitrenium Ions in Selected Solutions

Molecules, 2018
Nitrenium ions are important reactive intermediates in chemistry and biology. In this work, femtosecond and nanosecond transient absorption (fs-TA and ns-TA) along with nanosecond time-resolved resonance Raman (ns-TR3) experiments were employed to ...
Lili Du, Xin Lan, Zhiping Yan, Ruixue Zhu, David Lee Phillips   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Attosecond transient absorption spooktroscopy: a ghost imaging approach to ultrafast absorption spectroscopy

Physical Chemistry Chemical Physics, 2020
Recently demonstrated isolated attosecond XFEL pulses should allow the probing of ultrafast electron dynamics at X-ray wavelengths. The authors use ghost imaging to enable high-resolution transient absorption spectroscopy at fluctuating XFEL sources.
Taran Driver, Siqi Li, Elio G. Champenois, Joseph Duris, Daniel Ratner, Thomas J. Lane, Philipp Rosenberger, Andre Al-Haddad, Vitali Averbukh, Toby Barnard, Nora Berrah, Christoph Bostedt, Philip H. Bucksbaum, Ryan Coffee, Louis F. DiMauro, Li Fang, Douglas Garratt, Averell Gatton, Zhaoheng Guo, Gregor Hartmann, Daniel Haxton, Wolfram Helml, Zhirong Huang, Aaron LaForge, Andrei Kamalov, Matthias F. Kling, Jonas Knurr, Ming-Fu Lin, Alberto A. Lutman, James P. MacArthur, Jon P. Marangos, Megan Nantel, Adi Natan, Razib Obaid, Jordan T. O'Neal, Niranjan H. Shivaram, Aviad Schori, Peter Walter, Anna Li Wang, Thomas J. A. Wolf, Agostino Marinelli, James P. Cryan   +41 more
openaire   +8 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Characterizing ultrashort pulses with photon energies above 1.12 eV based on transient absorption in silicon thin films

JPhys Photonics
Frequency-resolved optical switching (FROSt) is a phase-matching-free characterization technique for ultrashort pulses based on transient absorption in semiconductors.
Mayank Kumar, Saadat Mokhtari, Tristan Guay, Adrien Leblanc, Kosta Oubrerie, Sohail A Jalil, Elissa Haddad, Gaëtan Jargot, Philippe Lassonde, Heide Ibrahim, Giulio Vampa, François Légaré   +11 more
doaj   +1 more source

Transient absorption spectroscopy

, 2021
Die optischen Eigenschaften von organischen Farbstoffen und optisch aktiven anorganischen Molekülen werden durch ihre chemische Struktur, ihrer chemischer Umgebung, und durch das Verhalten ihrer angeregten Zustände bestimmt. Die klassischen Methoden zur Untersuchung dieser Eigenschaften sind die Absorptions- und Lumineszenzspektroskopie.
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source