Results 241 to 250 of about 10,940,857 (293)

Transient Receptor Potential Melastatin 4 (TRPM4) is associated with an immuno-stimulatory TME and better prognosis in BLCA. [PDF]

Discov Oncol
Da Y, Chen X, Yu L, Li Y, Chen Z, Zhang Y, Wang H, Zhu Z, Liu Y, Geng Y.   +9 more
europepmc   +1 more source

Poly(ADP-ribose) polymerase regulates transient receptor potential channel M2-dependent calpain activation in rd1 mouse retinal degeneration. [PDF]

Neural Regen Res
Yan J, Kong L, Zhao Z, Yang Q, Wang L, Yang Q, Harteneck C, Jiao K, Hu Z, Paquet-Durand F.   +9 more
europepmc   +1 more source

Tooth Pulp Afferents and Transient Receptor Potential (TRP) Ion Channels as Key Regulators of Pulp Homeostasis, Inflammation, and Pain. [PDF]

Int J Mol Sci
Chung MK, Raman S, Szallasi A.
europepmc   +1 more source

Integrative genomic, phylogenetic, and transcriptomic analyses reveal temperature-responsive transient receptor potential (TRP) genes in Pacific abalone Haliotis discus hannai. [PDF]

BMC Ecol Evol
Kim MA, Sohn YC.
europepmc   +1 more source

Transient receptor potential vanilloid 3 activation accelerates keratinocyte migration in vitro but not dermal wound healing in vivo. [PDF]

Mol Pharmacol
Zosel C, Krause AK, Müglitz A, Zuo YQ, Krügel U, Schaefer M.   +5 more
europepmc   +1 more source

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Transient receptor potential channelopathies

Pflügers Archiv - European Journal of Physiology, 2010
In the past years, several hereditary diseases caused by defects in transient receptor potential channels (TRP) genes have been described. This review summarizes our current knowledge about TRP channelopathies and their possible pathomechanisms. Based on available genetic indications, we will also describe several putative pathological conditions in ...
Bernd, Nilius, Grzegorz, Owsianik
openaire   +2 more sources

Transient receptor potential channels meet phosphoinositides [PDF]

EMBO Journal, 2008
Transient receptor potential (TRP) cation channels are unique cellular sensors that are involved in multiple cellular functions, ranging from transduction of sensory signals to the regulation of Ca(2+) and Mg(2+) homoeostasis. Malfunctioning of TRP channels is now recognized as the cause of several hereditary and acquired human diseases. At the time of
Thomas Voets, Bernd Nilius, Grzegorz Owsianik   +2 more
exaly   +4 more sources

Transient Receptor Potential A1 Modulators

Current Topics in Medicinal Chemistry, 2011
TRPA1 is a member of a superfamily of non-selective cation channels that is known to be involved in multiple physiological functions. TRPA1 is activated by a broad spectrum of chemical irritants and endogenous inflammatory compounds. An emerging role for TRPA1 in mediating pain and inflammation raises the possibility that compounds targeting TRPA1 ...
Tim, Strassmaier, Rajagopal, Bakthavatchalam   +1 more
openaire   +2 more sources

Transient Receptor Potential Channels and Mechanosensation

Annual Review of Neuroscience, 2013
Transient receptor potential (TRP) channels act as sensors for a range of stimuli as diverse as light, sound, touch, pheromones, and tissue damage. Their role in mechanosensation in the animal kingdom, identified by gene ablation studies, has raised questions about whether they are directly mechanically gated, whether they act alone or in concert with ...
Niels, Eijkelkamp, Kathryn, Quick, John N, Wood   +2 more
openaire   +2 more sources

Transient Receptor Potentials (TRPs) and Anaphylaxis

Current Allergy and Asthma Reports, 2012
The transient receptor potential (TRP) superfamily consists of 28 members in mammals (27 in human) that act as polymodal sensors and ion channels. They regulate cellular calcium influx, generate depolarization thereby triggering voltage dependent cellular processes, and in turn they are critical in inducing the metabolic activities of cells.
Smith, Peter K, Nilius, Bernd
openaire   +3 more sources