Results 261 to 270 of about 10,401,010 (296)

Transient receptor potential channels as drug targets

Expert Opinion on Therapeutic Targets, 2007
The mammalian transient receptor potential (TRP) superfamily of ion channels consists of voltage-independent, non-selective cation channels that are expressed in excitable and non-excitable cells. The biologic roles of TRP channels are diverse and include vascular tone, thermosensation, irritant stimuli sensing and flow sensing in the kidney.
Dayne Y, Okuhara, Albert Y, Hsia, Michael, Xie   +2 more
openaire   +2 more sources

Transient receptor potential channels and occupational exposure

Current Opinion in Allergy & Clinical Immunology, 2014
The discovery that a number of transient receptor potential (TRP) channels are expressed in a subpopulation of primary sensory neurons innervating the upper and lower airways as well as in nonneuronal cells in the airways and lungs has initiated a quest for the understanding of their role in the physiology and pathophysiology of the respiratory tract ...
Geppetti P, Patacchini R, Nassini R.
openaire   +2 more sources

Brain transient receptor potential channels and stroke

Journal of Neuroscience Research, 2014
Transient receptor potential (TRP) channels have been increasingly implicated in the pathological mechanisms of CNS disorders. TRP expression has been detected in neurons, astrocytes, oligodendrocytes, microglia, and ependymal cells as well as in the cerebral vascular endothelium and smooth muscle.
Eric, Zhang, Ping, Liao
openaire   +2 more sources

Transient Receptor Potential Channels

2011
Volume 696 SOFTWARE TOOLS AND ALGORITHMS FOR BIOLOGICALSYSTEMSEdited by Hamid R. Arabnia and Quoc-Nam TranVolume 697 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN VIIEdited by Andrew Pollard, Adam Finn, and Nigel CurtisVolume 698 BIO-FARMS FOR NUTRACEUTICALS: FUNCTIONAL FOODAND SAFETY CONTROL BY BIOSENSORSMaria Teresa Giardi, Giuseppina Rea and ...
openaire   +1 more source

Transient Receptor Potential Channels in neuropathic pain

Current Opinion in Pharmacology, 2017
Neuropathic pain caused by disease or dysfunction of the nervous system is one of the most difficult pain conditions to treat. Symptoms include a hypersensitivity to mechanical and thermal stimuli, processed by specialized nociceptors that constitute the first line of defence of the somatosensory system.
Lilian, Basso, Christophe, Altier
openaire   +2 more sources

Transient Receptor Potential Channels, the Kidney and Hypertension

Current Hypertension Reviews, 2006
Smooth muscle cells as well as non-excitable cells express multiple cationic channels with significant permeability to calcium, potassium and sodium. Several of these channels are sensors of calcium store depletion, G-protein coupled receptor activation, membrane stretch, intracellular Ca2+, pH, oxidative stress, phospholipid signals and other factors.
openaire   +1 more source

Transient Receptor Potential

2006
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Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Hope Rugo, Laura Huppert
exaly  

Transient and receptor potentials in the electroretinogram ofDrosophila

Vision Research, 1972
W S, Stark, G S, Wasserman
openaire   +2 more sources

Transient receptor potential (TRP)

British Journal of Pharmacology, 2006
S P H Alexander, A Mathie, J A Peters
openaire   +1 more source