Results 121 to 130 of about 1,668,806 (304)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Application of fuzzy controllers in the autopilot of an unmanned aerial vehicle

Системный анализ и прикладная информатика
The article is devoted to the study of the features of the application of regulators built on the use of theoretical provisions of fuzzy logic, when creating autopilots of unmanned aerial vehicles (UAVs).
Penghao Gu, A. A. Lobaty
doaj   +1 more source

Transient Response and Firing Behaviors of Memristive Neuron Circuit. [PDF]

Front Neurosci, 2022
Fang X, Tan Y, Zhang F, Duan S, Wang L.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Transient response of bridge piers under eccentric impact of near-fault earthquake. [PDF]

Sci Rep, 2022
Wang Z, Zeng Q, Du Y, An W.
europepmc   +1 more source

Transient analysis using conical shell elements [PDF]

, 1973
The use of the NASTRAN conical shell element in static, eigenvalue, and direct transient analyses is demonstrated. The results of a NASTRAN static solution of an externally pressurized ring-stiffened cylinder agree well with a theoretical discontinuity ...
Goeller, J. E., Messick, W. T., Yang, J. C. S.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Fast-Transient-Response NMOS LDO with Wide Load-Capacitance Range for Cross-Point Memory. [PDF]

Sensors (Basel), 2022
He L, Li X, Xu S, Pan G, Xie C, Chen H, Song Z.   +6 more
europepmc   +1 more source

Calculation of transient response

Electronics Letters, 1968
Given the rational algebraic function X(s) = an−1Sn−1+an−2Sn−2+…+a1s+a0/sn+bn−1sn−1+…+b1s+b0 it is shown that the corresponding time function is expressed simply by the linear combination x(t) = an−1qn−1(t)+an−2qn−2(t) +… +a1q1(t) + a0q0(t) where functions qt(t) are the last column elements of the transition matrix M(t) = exp (At).
openaire   +1 more source

Transient upsets in microprocessor controllers [PDF]

The modeling and analysis of transient faults in microprocessor based controllers are discussed. Such controllers typically consist of a microprocessor, read only memory storing and application program, random access memory for data storage, and input ...
Glaser, R. E., Masson, G. M.
core   +1 more source