Results 111 to 120 of about 804,926 (346)

The gamma-ray observatory [PDF]

open access: yes, 1991
An overview is given of the Gamma Ray Observatory (GRO) mission. Detection of gamma rays and gamma ray sources, operations using the Space Shuttle, and instruments aboard the GRO, including the Burst and Transient Source Experiment (BATSE), the Oriented ...

core   +1 more source

Prospects for Galactic transient sources detection with the Cherenkov Telescope Array [PDF]

open access: hybrid, 2021
A. López-Oramas   +19 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Electrical discharge source for tropospheric “ozone‐rich transients”

open access: yesJournal of Geophysical Research: Atmospheres, 2002
In situ trace gas (O3, NO, NO2, NOy) and ultrafine aerosol particle data from a passenger aircraft (project CARIBIC) and the NOAA WP‐3D research aircraft are used to identify the origin of “ozone‐rich transients” that occasionally appear in aircraft ozone data sets along flight distances of 5–80 km.
Zahn, A.   +9 more
openaire   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Varying Activity and the Burst Properties of FRB 20240114A Probed with GMRT Down to 300 MHz

open access: yesThe Astrophysical Journal
Repeating fast radio bursts (FRBs) can exhibit a wide range of burst repetition rates, from none to hundreds of bursts per hour. Here we report the detection and characteristics of 60 bursts from the recently discovered FRB 20240114A, observed with the ...
Ajay Kumar, Yogesh Maan, Yash Bhusare
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A Time-domain Study of Repeat and Nonrepeat Fast Radio Bursts

open access: yesThe Astrophysical Journal
Fast radio bursts (FRBs) are extremely energetic radio transients, typically classified as repeat or nonrepeat, but their origins remain uncertain. In this work, we focus on the timing characteristics of the pulses in 536 FRBs observed by CHIME with ...
Zheng-Huo Jiang   +6 more
doaj   +1 more source

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