Results 131 to 140 of about 788,774 (301)
The Astrophysical JournalConstrained measurements of fundamental physical constants using astronomical observational data represent a powerful method for investigating potential new physics. In particular, the dispersion measure (DM) of fast radio bursts (FRBs), which probes the
Shi-Yuan Wang, Jun-Qing Xia
doaj +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Can Repeating and Nonrepeating Fast Radio Bursts Be Drawn from the Same Population?
The Astrophysical JournalDo all fast radio burst (FRB) sources repeat? We present evidence that FRB sources follow a Zipf-like distribution, in which the number density of sources is approximately inversely proportional to their burst rate above a fixed energy threshold—even ...
Paz Beniamini, Pawan Kumar
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Transient Thermal and Analytical Model of Whirling Process Based on Time-varying Heat Source in Machining Screw [PDF]
, 2018 Yan He
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A Unified Volumetric Rate–Energy Relation from Magnetar Radio Bursts to Fast Radio Bursts
The Astrophysical JournalFast radio bursts (FRBs) are millisecond radio pulses with extremely high bright temperature. Their physical origin is still a mystery. The discovery of FRB 20020428 supports the idea that at least a portion of FRBs is generated by magnetars.
Hao-Tian Lan, Shuang-Xi Yi, Fa-Yin Wang
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FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
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Constraining Baryonic Feedback Effects on the Matter Power Spectrum with Fast Radio Bursts
The Astrophysical JournalIn the age of large-scale galaxy and lensing surveys, such as DESI, Euclid, Roman, and Rubin, we stand poised to usher in a transformative new phase of data-driven cosmology. To fully harness the capabilities of these surveys, it is critical to constrain
Isabel Medlock +3 more
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Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source