Results 71 to 80 of about 804,926 (346)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Eight Years of Light from ASASSN-15oi: Toward Understanding the Late-time Evolution of TDEs

The Astrophysical Journal
We present results from an extensive follow-up campaign of the tidal disruption event (TDE) ASASSN-15oi spanning δt  ∼ 10–3000 days, offering an unprecedented window into the multiwavelength properties of a TDE during its first ≈8 yr of evolution. ASASSN-
A. Hajela, K. D. Alexander, R. Margutti, R. Chornock, M. Bietenholz, C. T. Christy, M. Stroh, G. Terreran, R. Saxton, S. Komossa, J. S. Bright, E. Ramirez-Ruiz, D. L. Coppejans, J. K. Leung, Y. Cendes, E. Wiston, T. Laskar, A. Horesh, G. Schroeder, Nayana A. J., M. H. Wieringa, N. Velez, E. Berger, P. K. Blanchard, T. Eftekhari, S. Gomez, M. Nicholl, H. Sears, B. A. Zauderer   +28 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Effect of the Velocity Distribution on Kilonova Emission

The Astrophysical Journal
The electromagnetic emission from the nonrelativistic ejecta launched in neutron star mergers (either dynamically or through a disk wind) has the potential to probe both the total mass and composition of this ejecta.
Chris L. Fryer, Aimee L. Hungerford, Ryan T. Wollaeger, Jonah M. Miller, Soumi De, Christopher J. Fontes, Oleg Korobkin, Atul Kedia, Marko Ristic, Richard O’Shaughnessy   +9 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The Radio Counterpart to the Fast X-Ray Transient EP240414a

The Astrophysical Journal
Despite being operational for only a short time, the Einstein Probe mission, with its large field of view and rapid localization capabilities, has already significantly advanced the study of rapid variability in the soft X-ray sky.
Joe S. Bright, Francesco Carotenuto, Rob Fender, Carmen Choza, Andrew Mummery, Peter G. Jonker, Stephen J. Smartt, David R. DeBoer, Wael Farah, James Matthews, Alexander W. Pollak, Lauren Rhodes, Andrew Siemion   +12 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Nature of Optical Afterglows without Gamma-Ray Bursts: Identification of AT2023lcr and Multiwavelength Modeling

The Astrophysical Journal
In the past few years, the improved sensitivity and cadence of wide-field optical surveys have enabled the discovery of several afterglows without associated detected gamma-ray bursts (GRBs).
Maggie L. Li, Anna Y. Q. Ho, Geoffrey Ryan, Daniel A. Perley, Gavin P. Lamb, Nayana A.J., Igor Andreoni, G. C. Anupama, Eric C. Bellm, Edo Berger, Joshua S. Bloom, Eric Burns, Ilaria Caiazzo, Poonam Chandra, Michael W. Coughlin, Kareem El-Badry, Matthew J. Graham, Mansi Kasliwal, Garrett K. Keating, S. R. Kulkarni, Harsh Kumar, Frank J. Masci, Richard A. Perley, Josiah Purdum, Ramprasad Rao, Antonio C. Rodriguez, Ben Rusholme, Nikhil Sarin, Jesper Sollerman, Gokul P. Srinivasaragavan, Vishwajeet Swain, Zachary Vanderbosch   +31 more
doaj   +1 more source

The Excess Radio Background and Fast Radio Transients

, 2015
In the last few years ARCADE 2, combined with older experiments, has detected an additional radio background, measured as a temperature and ranging in frequency from 22 MHz to 10 GHz, not accounted for by known radio sources and the cosmic microwave ...
Kehayias, John, Kephart, Thomas W., Weiler, Thomas J.   +2 more
core   +1 more source