Results 91 to 100 of about 13,276,015 (255)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Observations and Studies on the Transiting Systems HAT-P-36, XO-2 and WASP-76

The Astronomical Journal
We conducted photometric observations for transit events of three exoplanetary systems HAT-P-36, XO-2 and WASP-76 using the 1 m and 2.4 m telescopes at Yunnan Observatories and the 0.85 m telescope at National Astronomical Observatories of China.
Weilong Wang, Shenghong Gu, Xiaobin Wang, Leilei Sun, Byeong-Cheol Lee, Chi-Tai Kwok, Ho-Keung Hui, Jiangpei Dou, Yue Xiang, Dongtao Cao, Fukun Xu   +10 more
doaj   +1 more source

NJ Transit Minutes

, 2020
Downloaded from: https://www.njtransit.com/board-meeting-minutes Minutes, Covid survey presentation and Transit grid presentation are in separate ...
NJ Transit
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Analyzing the Costs of Operating Small Transit Vehicles: User\u27s Guide STVe (Small Transit Vehicle economics)

, 2000
This User\u27s Guide explains the accompanying Small Transit Vehicle economics (STVe) model - a tool designed for transit planners and others making decisions about the purchase of small transit vehicles for different services and operating environments.
Transportation Research Board, Laidlaw Transit Services, Incorpor, Littleton C MacDorman, KFH Group, Incorporated   +3 more
core   +2 more sources

A Combined TESS and Ground-based Study of Transit Timing Variations in HAT-P-16, TOI-1516 and TOI-2046 Systems

The Astronomical Journal
We present new results for the hot Jupiters HAT-P-16b, TOI-1516b, and TOI-2046b, based on photometric observations collected using both space- and ground-based facilities.
E. Sonbas, K. Kaplan, M. Tanriver, A. Keskin, K. Dhuga, A. Bulut, E. Göğüş, W. Ogłoza   +7 more
doaj   +1 more source

National RTAP's Resource Share Curation Project: Development of a Collection Tailored Toward Rural and Tribal Transit Technical Assistance [PDF]

This poster was presented at the 2018 TRB Annual Meeting.Research shows that the organizational mission, priorities and user are the most important factors of collection development for transportation libraries.
Marcus, Cara, National Rural Transit Assistance Program (U.S.), Phillips, Robin   +2 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Updated Masses for the Gas Giants in the Eight-planet Kepler-90 System Via Transit-timing Variation and Radial Velocity Observations

The Astronomical Journal
The eight-planet Kepler-90 system exhibits the greatest multiplicity of planets found to date. All eight planets are transiting and were discovered in photometry from the NASA Kepler primary mission. The two outermost planets, g ( P _g  = 211 days) and h
David E. Shaw, Lauren M. Weiss, Eric Agol, Karen A. Collins, Khalid Barkaoui, Cristilyn N. Watkins, Richard P. Schwarz, Howard M. Relles, Chris Stockdale, John F. Kielkopf, Fabian Rodriguez Frustaglia, Allyson Bieryla, Joao Gregorio, Owen Mitchem, Katherine Linnenkohl, Adam Popowicz, Norio Narita, Akihiko Fukui, Michaël Gillon, Ramotholo Sefako, Avi Shporer, Adam Lark, Amelie Heying, Isa Khan, Beibei Chen, Kylee Carden, Donald M. Terndrup, Robert Taylor, Dasha Crocker, Sarah Ballard, Daniel C. Fabrycky   +30 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source