Results 71 to 80 of about 6,653 (227)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigation of Transit Timing and an Optical Transmission Spectrum of the Hot Jupiter WASP-11 b
The Astronomical JournalWASP-11 b/HAT-P-10 b is an inflated hot Jupiter, which has a low density that makes it a good target for atmospheric studies using the transmission spectroscopy technique.
Napaporn A-thano +17 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Observations and Studies on the Transiting Systems HAT-P-36, XO-2 and WASP-76
The Astronomical JournalWe conducted photometric observations for transit events of three exoplanetary systems HAT-P-36, XO-2 and WASP-76 using the 1 m and 2.4 m telescopes at Yunnan Observatories and the 0.85 m telescope at National Astronomical Observatories of China.
Weilong Wang +10 more
doaj +1 more source
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
The Astronomical JournalWe present new results for the hot Jupiters HAT-P-16b, TOI-1516b, and TOI-2046b, based on photometric observations collected using both space- and ground-based facilities.
E. Sonbas +7 more
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
The Astronomical JournalThe eight-planet Kepler-90 system exhibits the greatest multiplicity of planets found to date. All eight planets are transiting and were discovered in photometry from the NASA Kepler primary mission. The two outermost planets, g ( P _g = 211 days) and h
David E. Shaw +30 more
doaj +1 more source