Results 61 to 70 of about 13,276,015 (255)
A Transiting Giant on a 7.7 yr Orbit Revealed by Transit Timing Variations in the TOI-201 System
The Astrophysical Journal LettersWe report the detection and characterization of TOI-201 c, a long-period transiting companion to the warm Jupiter TOI-201 b. Its presence was first inferred from high-amplitude transit timing variations (TTVs) in TOI-201 b, pointing to a massive outer ...
Gracjan Maciejewski, Weronika Łoboda
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Validation of a Third Planet in the LHS 1678 System
The Astronomical JournalThe nearby LHS 1678 (TOI-696) system contains two confirmed planets and a wide-orbit, likely brown-dwarf companion, which orbit an M2 dwarf with a unique evolutionary history. The host star occupies a narrow “gap” in the Hertzsprung–Russell diagram lower
Michele L. Silverstein +26 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Astronomical JournalThe ExoEcho project is designed to study the photodynamics of exoplanets by leveraging high-precision transit timing data from ground- and space-based telescopes.
Xinyue Ma +8 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
, 2013 Transit agencies wishing to offer reliable service with less variability compared to schedules face several challenges, encouraging them to employ various strategies.
El-Geneidy, Ahmed M., Diab, Ehab I.
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Doomed Worlds. I. No New Evidence for Orbital Decay in a Long-term Survey of 43 Ultrahot Jupiters
The Planetary Science JournalUltrahot Jupiters (UHJs) are likely doomed by tidal forces to undergo orbital decay and eventual disruption by their stars, but the timescale over which this process unfolds is unknown. We present results from a long-term project to monitor UHJ transits.
Elisabeth R. Adams +10 more
doaj +1 more source
Process variation-aware test for resistive bridges [PDF]
, 2009 This paper analyses the behaviour of resistive bridging faults under process variation and shows that process variation has a detrimental impact on test quality in the form of test escapes.
Ingelsson, Urban +6 more
core +1 more source