Results 61 to 70 of about 6,653 (227)
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Inferring Exoplanet Parameters from Transit Timing Variations Using LSTM Networks
The Planetary Science JournalTransit timing variation (TTV) analysis provides a valuable complement to traditional transit and radial-velocity techniques, particularly in compact, near-resonant planetary systems where dynamical interactions amplify timing signals and refine mass and
Muhammad Isnaenda Ikhsan +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Decade of Transit-timing Measurements Confirm Resonance in the K2-19 System
The Astronomical JournalK2-19 is a star, slightly smaller than the Sun, that hosts three transiting planets. Two of these, K2-19 b and c, are between the size of Neptune and Saturn and have orbital periods near a 3:2 commensurability, and exhibit strong transit-timing ...
Paige M. Entrican +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Ground-based Transit Observation of the Long-period Extremely Low-density Planet HIP 41378 f
The Astronomical JournalWe present a ground-based transit detection of HIP 41378 f, a long-period ( P = 542 days), extremely low-density (0.09 ± 0.02 g cm ^−3 ) giant exoplanet in a dynamically complex system.
Juliana García-Mejía +27 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Updated Mass, Eccentricity, and Tidal Heating Constraints for the Earth-sized Planet LP 791-18 d
The Astronomical JournalLP 791-18 d is a temperate Earth-sized planet ( R _P = 1.03 R _⊕ , P = 2.76 days) orbiting a late M dwarf, with an interior super-Earth (LP 791-18 b, R _P = 1.2 R _⊕ , P = 0.95 days) and an exterior sub-Neptune (LP 791-18 c, R _P = 2.5 R _⊕ , P = 4.99 ...
Michael Greklek-McKeon +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Planet Candidate Orbiting near the Hot Jupiter TOI-2818 b Inferred through Transit Timing
The Astrophysical JournalTOI-2818 b is a hot Jupiter orbiting a slightly evolved G-type star on a 4.04 day orbit that shows transit timing variations (TTVs) suggestive of a decreasing orbital period. In the most recent year of TESS observations, transits were observed ∼8 minutes
Brendan J. McKee +7 more
doaj +1 more source