Results 61 to 70 of about 68,837 (213)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

TOI-4495: A Pair of Aligned, Near-resonant Sub-Neptunes That Likely Experienced Overstable Migration

The Astronomical Journal
We report the discovery of a sub-Neptune and a Neptune-like planet ( R ${}_{b}=2.4{8}_{-0.10}^{+0.14}$ R _⊕ , R ${}_{c}=4.0{3}_{-0.15}^{+0.23}$ R _⊕ ) orbiting the F-type star TOI-4495.
Mu-Tian Wang, Fei Dai, Hui-Gen Liu, Kento Masuda, Andrew W. Howard, Samuel Halverson, Howard Isaacson, Elina Y. Zhang, Max Goldberg, Huan-Yu Teng, Ryan A. Rubenzahl, Benjamin Fulton, Erik A. Petigura, Steven Giacalone, Luke Handley, David W. Latham, Allyson Bieryla, Ashley Baker, Jerry Edelstein, Steven R. Gibson, Kodi Rider, Arpita Roy, Chris Smith, Josh Walawender, David Rapetti, Jon M. Jenkins, Joshua N. Winn   +26 more
doaj   +1 more source

No variations in transit times for Qatar-1 b

, 2015
The transiting hot Jupiter planet Qatar-1 b was presented to exhibit variations in transit times that could be of perturbative nature. A hot Jupiter with a planetary companion on a nearby orbit would constitute an unprecedented planetary configuration ...
Aceituno, F. J., Dimitrov, D., Errman, R., Fernández, M., Gilbert, H., Kitze, M., Maciejewski, G., Neuhäuser, R., Ohlert, J., Pannicke, A., Puchalski, D., Raetz, St., Schmidt, J. -G., Seeliger, M.   +13 more
core   +1 more source

Broad-band spectrophotometry of the hot Jupiter HAT-P-12b from the near-UV to the near-IR [PDF]

, 2015
The detection of trends or gradients in the transmission spectrum of extrasolar planets is possible with observations at very low spectral resolution.
Bernt, I., Csizmadia, Sz., Dhillon, V. S., Granzer, T., Herrero, E., Künstler, A., Mallonn, M., Marsh, T. R., Nascimbeni, V., Pagano, I., Piotto, G., Sada, P. V., Scandariato, G., Strassmeier, K. G., von Essen, C., Weingrill, J.   +15 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Exoplanet Ephemerides Change Observations (ExoEcho). II. Transit Timing Variation Analysis of Brown Dwarfs around Solar-type Stars

The Astrophysical Journal
Transit timing variation (TTV) is a useful tool for studying the orbital properties of transiting objects. However, few TTV studies have been done on transiting brown dwarfs (BDs) around solar-type stars.
Wenqin Wang, Xinyue Ma, Zhangliang Chen, Cong Yu, Shangfei Liu, Bo Ma   +5 more
doaj   +1 more source

The Quasiperiodic Automated Transit Search Algorithm

, 2012
We present a new algorithm for detecting transiting extrasolar planets in time-series photometry. The Quasiperiodic Automated Transit Search (QATS) algorithm relaxes the usual assumption of strictly periodic transits by permitting a variable, but bounded,
Agol, Eric, Carter, Joshua A.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Transiting Giant on a 7.7 yr Orbit Revealed by Transit Timing Variations in the TOI-201 System

The Astrophysical Journal Letters
We report the detection and characterization of TOI-201 c, a long-period transiting companion to the warm Jupiter TOI-201 b. Its presence was first inferred from high-amplitude transit timing variations (TTVs) in TOI-201 b, pointing to a massive outer ...
Gracjan Maciejewski, Weronika Łoboda
doaj   +1 more source

Transit Timing Observations from Kepler. VIII Catalog of Transit Timing Measurements of the First Twelve Quarters

, 2013
Following Ford et al. (2011, 2012) and Steffen et al. (2012) we derived the transit timing of 1960 Kepler KOIs using the pre-search data conditioning (PDC) light curves of the first twelve quarters of the Kepler data. For 721 KOIs with large enough SNRs,
Agol, Eric, Carter, Joshua A., Fabrycky, Daniel C., Ford, Eric B., Holczer, Tomer, Lissauer, Jack J., Mazeh, Tsevi, Nachmani, Gil, Quintana, Elisa V., Ragozzine, Darin, Rowe, Jason F., Sanchis-Ojeda, Roberto, Sokol, Gil, Steffen, Jason H., Welsh, William, Zucker, Shay   +15 more
core   +1 more source