Results 31 to 40 of about 6,579 (217)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesThe presence of another planetary companion in a transiting exoplanet system can impact its transit light curve, leading to sinusoidal transit-timing variations (TTV).
Zixin Zhang +9 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
TOI-4495: A Pair of Aligned, Near-resonant Sub-Neptunes That Likely Experienced Overstable Migration
The Astronomical JournalWe report the discovery of a sub-Neptune and a Neptune-like planet ( R ${}_{b}=2.4{8}_{-0.10}^{+0.14}$ R _⊕ , R ${}_{c}=4.0{3}_{-0.15}^{+0.23}$ R _⊕ ) orbiting the F-type star TOI-4495.
Mu-Tian Wang +26 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Astrophysical JournalTransit timing variation (TTV) is a useful tool for studying the orbital properties of transiting objects. However, few TTV studies have been done on transiting brown dwarfs (BDs) around solar-type stars.
Wenqin Wang +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A Transiting Giant on a 7.7 yr Orbit Revealed by Transit Timing Variations in the TOI-201 System
The Astrophysical Journal LettersWe report the detection and characterization of TOI-201 c, a long-period transiting companion to the warm Jupiter TOI-201 b. Its presence was first inferred from high-amplitude transit timing variations (TTVs) in TOI-201 b, pointing to a massive outer ...
Gracjan Maciejewski, Weronika Łoboda
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Validation of a Third Planet in the LHS 1678 System
The Astronomical JournalThe nearby LHS 1678 (TOI-696) system contains two confirmed planets and a wide-orbit, likely brown-dwarf companion, which orbit an M2 dwarf with a unique evolutionary history. The host star occupies a narrow “gap” in the Hertzsprung–Russell diagram lower
Michele L. Silverstein +26 more
doaj +1 more source