Results 41 to 50 of about 5,805 (230)

Doomed Worlds. I. No New Evidence for Orbital Decay in a Long-term Survey of 43 Ultrahot Jupiters

open access: yesThe Planetary Science Journal
Ultrahot Jupiters (UHJs) are likely doomed by tidal forces to undergo orbital decay and eventual disruption by their stars, but the timescale over which this process unfolds is unknown. We present results from a long-term project to monitor UHJ transits.
Elisabeth R. Adams   +10 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Updated Mass, Eccentricity, and Tidal Heating Constraints for the Earth-sized Planet LP 791-18 d

open access: yesThe Astronomical Journal
LP 791-18 d is a temperate Earth-sized planet ( R _P = 1.03 R _⊕ , P = 2.76 days) orbiting a late M dwarf, with an interior super-Earth (LP 791-18 b, R _P = 1.2 R _⊕ , P = 0.95 days) and an exterior sub-Neptune (LP 791-18 c, R _P = 2.5 R _⊕ , P = 4.99 ...
Michael Greklek-McKeon   +7 more
doaj   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

A Planet Candidate Orbiting near the Hot Jupiter TOI-2818 b Inferred through Transit Timing

open access: yesThe Astrophysical Journal
TOI-2818 b is a hot Jupiter orbiting a slightly evolved G-type star on a 4.04 day orbit that shows transit timing variations (TTVs) suggestive of a decreasing orbital period. In the most recent year of TESS observations, transits were observed ∼8 minutes
Brendan J. McKee   +7 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Observations and Studies on the Transiting Systems HAT-P-36, XO-2 and WASP-76

open access: yesThe Astronomical Journal
We conducted photometric observations for transit events of three exoplanetary systems HAT-P-36, XO-2 and WASP-76 using the 1 m and 2.4 m telescopes at Yunnan Observatories and the 0.85 m telescope at National Astronomical Observatories of China.
Weilong Wang   +10 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

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