Results 61 to 70 of about 76,246 (270)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A Transiting Giant on a 7.7 yr Orbit Revealed by Transit Timing Variations in the TOI-201 System

The Astrophysical Journal Letters
We report the detection and characterization of TOI-201 c, a long-period transiting companion to the warm Jupiter TOI-201 b. Its presence was first inferred from high-amplitude transit timing variations (TTVs) in TOI-201 b, pointing to a massive outer ...
Gracjan Maciejewski, Weronika Łoboda
doaj   +1 more source

Investigating the physical properties of transiting hot Jupiters with the 1.5-m Kuiper Telescope

, 2017
We present new photometric data of 11 hot Jupiter transiting exoplanets (CoRoT-12b, HAT-P-5b, HAT-P-12b, HAT-P-33b, HAT-P-37b, WASP-2b, WASP-24b, WASP-60b, WASP-80b, WASP-103b, XO-3b) in order to update their planetary parameters and to constrain ...
Berube, Michael P., Biddle, Lauren I., Cates, Ian T., Cook, Kendall L., Hardegree-Ullman, Kevin K., Johnson, Robert E., Jones, Christen K., Leiter, Robin M., Nieberding, Megan N., Pearson, Kyle A., Raphael, Brandon, Teske, Johanna K., Thompson, Robert M., Turner, Jake D., Wallace, Spencer, Watson, Zachary T.   +15 more
core   +1 more source

Transit spectrophotometry of the exoplanet HD189733b. II. New Spitzer observations at 3.6 microns [PDF]

, 2010
We present a new primary transit observation of the hot-jupiter HD189733b, obtained at 3.6 microns with the Infrared Array Camera (IRAC) onboard the Spitzer Space Telescope.
A. Lecavelier des Etangs, A. Vidal-Madjar, Agol, Agol, Bakos, Bakos, Ballester, Beaulieu, Bouchy, Burrows, Burrows, Carter, Carter, Charbonneau, Charbonneau, Charbonneau, Croll, Czesla, D. Ehrenreich, D. Sing, Deming, Deming, Deming, Demory, Désert, Désert, Ehrenreich, Fazio, Fortney, Fortney, G. Hébrard, G. W. Henry, Gillon, Gillon, Grillmair, Grillmair, Henry, Hubbard, Hébrard, Hébrard, J.-M. Désert, Knutson, Knutson, Lecavelier des Etangs, Lecavelier des Etangs, Lecavelier des Etangs, Mandel, Miller-Ricci, Moutou, Nutzman, Pont, Pont, Pont, R. Ferlet, Redfield, Seager, Sharp, Sing, Sing, Sing, Sing, Southworth, Swain, Swain, Tinetti, V. Parmentier, Vidal-Madjar, Vidal-Madjar, Vidal-Madjar, Werner, Winn   +70 more
core   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Validation of a Third Planet in the LHS 1678 System

The Astronomical Journal
The nearby LHS 1678 (TOI-696) system contains two confirmed planets and a wide-orbit, likely brown-dwarf companion, which orbit an M2 dwarf with a unique evolutionary history. The host star occupies a narrow “gap” in the Hertzsprung–Russell diagram lower
Michele L. Silverstein, Thomas Barclay, Joshua E. Schlieder, Karen A. Collins, Richard P. Schwarz, Benjamin J. Hord, Jason F. Rowe, Ethan Kruse, Nicola Astudillo-Defru, Xavier Bonfils, Douglas A. Caldwell, David Charbonneau, Ryan Cloutier, Kevin I. Collins, Tansu Daylan, William Fong, Jon M. Jenkins, Michelle Kunimoto, Scott McDermott, Felipe Murgas, Enric Palle, George R. Ricker, Sara Seager, Avi Shporer, Evan Tey, Roland Vanderspek, Joshua N. Winn   +26 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A Modified Kwee–Van Woerden Method for Eclipse Minimum Timing with Reliable Error Estimates

Galaxies, 2020
The Kwee–van Woerden (KvW) method used for the determination of eclipse minimum times has been a staple in eclipsing binary research for decades, due its simplicity and the independence of external input parameters, which also makes it well-suited to ...
Hans J. Deeg
doaj   +1 more source

Photometric Follow-up Observations of the Transiting Neptune-Mass Planet GJ 436b

, 2008
This paper presents multi-band photometric follow-up observations of the Neptune-mass transiting planet GJ 436b, consisting of 5 new ground-based transit light curves obtained in May 2007. Together with one already published light curve we have at hand a
Avi Shporer, Barman, Burke, Burke, Butler, Charbonneau, Claret, David W. Latham, Deming, Fischer, Ford, Fortney, Frederic Pont, Gilbert A. Esquerdo, Gregory, Guillot, Holman, Joshua N. Winn, Mandel, Matthew J. Holman, Mazeh, Mazeh, Miralda Escudé, Pont, Ribas, Soderhjelm, Szentgyorgyi, Torres, Torres, Tsevi Mazeh, Winn, Winn   +31 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source