Results 71 to 80 of about 75,518 (268)

Quantifying the challenges of detecting unseen planetary companions with transit timing variations

, 2010
Both ground and space-based transit observatories are poised to significantly increase the number of known transiting planets and the number of precisely measured transit times.
Adams, Bakos, Capen, Coughlin, Deeg, Dimitri Veras, Dvorak, Díaz, Eric B. Ford, Fabrycky, Ford, Knutson, Laughlin, Lee, Lee, Mardling, Matthew J. Payne, Meschiari, Miller-Ricci, Miller-Ricci, Miralda-Escudé, Murray, Nesvorný, Nesvorný, Nesvorný, Payne, Payne, Ragozzine, Raymond, Sidlichovsky, Steffen, Steffen, Veras, Veras   +33 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A Decade of Transit-timing Measurements Confirm Resonance in the K2-19 System

The Astronomical Journal
K2-19 is a star, slightly smaller than the Sun, that hosts three transiting planets. Two of these, K2-19 b and c, are between the size of Neptune and Saturn and have orbital periods near a 3:2 commensurability, and exhibit strong transit-timing ...
Paige M. Entrican, Erik A. Petigura, Antoine C. Petit, Gregory J. Gilbert, Kento Masuda   +4 more
doaj   +1 more source

The Kepler-19 System: A Transiting 2.2 R_⊕ Planet and a Second Planet Detected via Transit Timing Variations [PDF]

, 2011
We present the discovery of the Kepler-19 planetary system, which we first identified from a 9.3 day periodic transit signal in the Kepler photometry. From high-resolution spectroscopy of the star, we find a stellar effective temperature T_(eff) = 5541 ±
Ballard, Sarah, Ciardi, David R.
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Updated Mass, Eccentricity, and Tidal Heating Constraints for the Earth-sized Planet LP 791-18 d

The Astronomical Journal
LP 791-18 d is a temperate Earth-sized planet ( R _P = 1.03 R _⊕ , P = 2.76 days) orbiting a late M dwarf, with an interior super-Earth (LP 791-18 b, R _P = 1.2 R _⊕ , P = 0.95 days) and an exterior sub-Neptune (LP 791-18 c, R _P = 2.5 R _⊕ , P = 4.99 ...
Michael Greklek-McKeon, Heather A. Knutson, W. Garrett Levine, Renyu Hu, Morgan Saidel, Jonathan Gomez Barrientos, Konstantin Batygin, Björn Benneke   +7 more
doaj   +1 more source

The Quasiperiodic Automated Transit Search Algorithm

, 2012
We present a new algorithm for detecting transiting extrasolar planets in time-series photometry. The Quasiperiodic Automated Transit Search (QATS) algorithm relaxes the usual assumption of strictly periodic transits by permitting a variable, but bounded,
Agol, Eric, Carter, Joshua A.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A Planet Candidate Orbiting near the Hot Jupiter TOI-2818 b Inferred through Transit Timing

The Astrophysical Journal
TOI-2818 b is a hot Jupiter orbiting a slightly evolved G-type star on a 4.04 day orbit that shows transit timing variations (TTVs) suggestive of a decreasing orbital period. In the most recent year of TESS observations, transits were observed ∼8 minutes
Brendan J. McKee, Benjamin T. Montet, Samuel W. Yee, Joel D. Hartman, Joshua N. Winn, Jorge H. C. Martins, André M. Silva, Alexander L. Wallace   +7 more
doaj   +1 more source

Methods for exomoon characterisation: combining transit photometry and the Rossiter-McLaughlin effect

, 2010
It has been suggested that moons around transiting exoplanets may cause observable signal in transit photometry or in the Rossiter-McLaughlin (RM) effect.
A. E. Simon, Agol, Arentoft, Asimov, Barnes, Bean, Bertelli, Boesgaard, Bouchy, Claret, Díaz, Gaudi, Gilliland, Girardi, Gy. M. Szabó, Ida, Jenkins, K. Szatmáry, Kennedy, Kipping, Kipping, Kipping, Kjeldsen, L. L. Kiss, Lagrange, Lewis, Li, Liebig, O'Toole, Pál, Queloz, Queloz, Rivera, Saar, Sartoretti, Simon, Simon, Szabó Gy., Triaud, Wagner, Wright   +40 more
core   +1 more source