Results 71 to 80 of about 76,246 (270)

Exoplanet Ephemerides Change Observations (ExoEcho). I. Transit Timing Analysis of 37 Exoplanets Using HST/WFC3 Data

The Astronomical Journal
The ExoEcho project is designed to study the photodynamics of exoplanets by leveraging high-precision transit timing data from ground- and space-based telescopes.
Xinyue Ma, Wenqin Wang, Zixin Zhang, Cong Yu, Dichang Chen, Jiwei Xie, Shangfei Liu, Li Zhou, Bo Ma   +8 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Doomed Worlds. I. No New Evidence for Orbital Decay in a Long-term Survey of 43 Ultrahot Jupiters

The Planetary Science Journal
Ultrahot Jupiters (UHJs) are likely doomed by tidal forces to undergo orbital decay and eventual disruption by their stars, but the timescale over which this process unfolds is unknown. We present results from a long-term project to monitor UHJ transits.
Elisabeth R. Adams, Brian Jackson, Amanda A. Sickafoose, Jeffrey P. Morgenthaler, Hannah Worters, Hailey Stubbers, Dallon Carlson, Sakhee Bhure, Stijn Dekeyser, Chelsea X. Huang, Nevin N. Weinberg   +10 more
doaj   +1 more source

The Quasiperiodic Automated Transit Search Algorithm

, 2012
We present a new algorithm for detecting transiting extrasolar planets in time-series photometry. The Quasiperiodic Automated Transit Search (QATS) algorithm relaxes the usual assumption of strictly periodic transits by permitting a variable, but bounded,
Agol, Eric, Carter, Joshua A.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Super-Earths: A New Class of Planetary Bodies

, 2011
Super-Earths, a class of planetary bodies with masses ranging from a few Earth-masses to slightly smaller than Uranus, have recently found a special place in the exoplanetary science.
Armitage P. J., Christensen U. R., Clubb K., Dobrovolskis A. R., Fogg M. J., Ford E.B., Goldreich P., Haghighipour N., Haghighipour N., Hatzes A.P., Heng K., Michael S., Nader Haghighipour, Safronov V. S., Smoluchowski M. V., Sotin C., Stamenkovic V., Stamenkovic V., Steffen J. H., Swift D. C., Tackley P. J., Weidenschilling S. J.   +21 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Accounting for Transit Timing Detectability: Biases in Planetary Radius and Orbital Period

The Astronomical Journal
Transit Timing Variations (TTVs) are deviations from the time an observer would expect to see an exoplanet transit its host star. In multiplanetary systems, significant TTVs may indicate the presence of another body in the system gravitationally ...
Skylar D’Angiolillo, Daniel Fabrycky, Mariah G. MacDonald   +2 more
doaj   +1 more source

Transit Photometry as an Exoplanet Discovery Method

, 2018
Photometry with the transit method has arguably been the most successful exoplanet discovery method to date. A short overview about the rise of that method to its present status is given.
A Collier Cameron, A Collier Cameron, A Giménez, A Léger, A Santerne, A Shporer, A Udalski, AMS Smith, Andrew Collier Cameron, B Tingley, BE McArthur, C Elachi, C Moutou, C Régulo, CA Haswell, D Bayliss, D Charbonneau, D Charbonneau, D Koch, D Queloz, D. J. Christian, DL Pollacco, DM Kipping, DW Latham, DW Latham, F Bouchy, F Pont, FT O’Donovan, G Kovács, G Kovács, G Torres, G Torres, G Torres, GR Ricker, GW Henry, GÁ Bakos, H Rauer, H. Parviainen, HJ Deeg, HJ Deeg, HJ Deeg, HJ Deeg, IAG Snellen, J Scalo, J. Cabrera, JA Dittmann, Jason F. Rowe, Jeffrey L. Coughlin, JJ Lissauer, JJ Lissauer, JJ Lissauer, JM Almenara, JM Jenkins, JM Jenkins, JM Jenkins, JN Winn, JT Wright, K Horne, K Mandel, KC Sahu, LR Doyle, M Gillon, M Konacki, MN Günther, MN Günther, NM Batalha, O Struve, O Tamuz, P Barge, PJ Wheatley, PJ Wheatley, R Alonso, R Alonso, R Alonso, RF Díaz, RL Gilliland, RL Gilliland, S Aigrain, S Aigrain, S Jha, S Seager, SB Howell, Smith AMS WASP Consortium, TD Morton, TD Morton, TG Beatty, TM Brown, WJ Borucki, ZK Berta   +88 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source