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Functional Flexibility of the Transketolase Molecule

Biochemistry (Moscow), 2001
Transketolase is the simplest representative of the thiamine diphosphate-dependent enzymes. It was the first of these enzymes for which X-ray analysis was performed. Based on the data of X-ray studies and using the mutagenesis technique, the nature of functional groups of the enzyme involved in the interaction with substrates and cofactors and in the ...
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Erythrocyte Transketolase Activity

The American Journal of Clinical Nutrition, 1970
Y H, Chong, G S, Ho
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Erythrocyte Transketolase Inhibition, Neuropathy and Uremia

New England Journal of Medicine, 1971
The first clinically successful treatment of renal failure with the artificial kidney by W. J. Kolff in 1943 must be regarded as an empirical triumph. Although several normal solutes had been identified in abnormally high concentration in the blood of uremic patients, there was no information about whether reducing their concentrations would restore ...
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Transketolase in blood

Clinica Chimica Acta, 1964
H, SCHOUTEN   +2 more
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Multiple forms of transketolase.

Biochemistry international, 1991
The multiplicity of transketolase forms, differing in thermostability and separated by phosphocellulose chromatography, has been shown. Using SDS-PAGE, it was found that the mobility of yeast enzyme forms in all cases was identical. Certain forms of transketolase from yeast, rat or pig liver and from some organs of the rabbit were similar with regard ...
A, Kuimov, M, Filippov, G, Kochetov
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[89] Transketolase: Clinical aspects

1966
Erythrocyte transketolase activity and the “TTP-effect” present a functional evaluation which is both sensitive to, and specific for, thiamine deficiency. It may be used to confirm clinical beriberi or other manifestations such as Wernicke's encephalopathy, to reveal a biochemical defect in marginal B1 deficiency, or to differentiate B1 deficiency from
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Transketolase

1996
Dietmar Schomburg, Dörte Stephan
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Transketolase in sickle cell anemia

Clinica Chimica Acta, 1971
H, Schouten   +2 more
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