Results 111 to 120 of about 5,388,665 (365)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The effectiveness of guideline implementation strategies in the dental setting: a systematic review

open access: yesImplementation Science, 2019
Background Guideline implementation has been an ongoing challenge in the dental practice setting. Despite this, there are no reviews summarising the existing evidence regarding effective guideline implementation strategies in this setting.
Amy R. Villarosa   +5 more
doaj   +1 more source

A Study on the Influence of Local Top Leaders' Corruption——An Empirical Analysis Based on the Municipal Party Committee Secretaries Sacked after the Eighteenth National Congress of the Communist Party of China

open access: yesContemporary Social Sciences, 2017
Based on the cross-sectional data about the municipal Party committee secretaries sacked since the 18th CPC National Congress, this paper adopts a regression model to examine and assess the impact of local top Party leaders’ corruption.
Liao Chongxu, Li Huoqiang, Zhou Dong
doaj   +1 more source

Recognition and translation Arabic-French of Named Entities: case of the Sport places [PDF]

open access: yes, 2009
The recognition of Arabic Named Entities (NE) is a problem in different domains of Natural Language Processing (NLP) like automatic translation. Indeed, NE translation allows the access to multilingual in-formation.
Fehri, Héla   +2 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Delivering the National Diabetes Prevention Program: Assessment of Retention, Physical Activity, and Weight Loss Outcomes by Participant Characteristics and Delivery Modes

open access: yesJournal of Diabetes Research
Type 2 diabetes disproportionately affects older adults, persons from racial and ethnic minority groups, and persons of low socioeconomic status. It can be prevented or delayed through evidence-based interventions such as the National Diabetes Prevention
Boon Peng Ng   +3 more
doaj   +1 more source

DEFINITION OF TRANSLATION, TRANSLATION STRATEGY, TRANSLATION PROCEDURE, TRANSLATION METHOD, TRANSLATION TECHNIQUE, TRANSLATION TRANSFORMATION

open access: yesInterConf, 2021
In modern linguistics, one of the current topics is the study of the relationships between languages, as one of the main means of transmission of meanings and the socio-cultural reality. Among the many challenges studied by the modern linguistics, an important place is the study of the linguistic aspects of cross-language speech activity, which is ...
openaire   +2 more sources

Learning Semantic Representations for the Phrase Translation Model [PDF]

open access: yes, 2013
This paper presents a novel semantic-based phrase translation model. A pair of source and target phrases are projected into continuous-valued vector representations in a low-dimensional latent semantic space, where their translation score is computed by ...
Deng, Li   +3 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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