Results 111 to 120 of about 5,227,080 (312)

The effectiveness of guideline implementation strategies in the dental setting: a systematic review

open access: yesImplementation Science, 2019
Background Guideline implementation has been an ongoing challenge in the dental practice setting. Despite this, there are no reviews summarising the existing evidence regarding effective guideline implementation strategies in this setting.
Amy R. Villarosa   +5 more
doaj   +1 more source

TransBooster: boosting the performance of wide-coverage machine translation systems [PDF]

open access: yes, 2005
We propose the design, implementation and evaluation of a novel and modular approach to boost the translation performance of existing, wide-coverage, freely available machine translation systems based on reliable and fast automatic decomposition of the ...
Khasin, Anna   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Delivering the National Diabetes Prevention Program: Assessment of Retention, Physical Activity, and Weight Loss Outcomes by Participant Characteristics and Delivery Modes

open access: yesJournal of Diabetes Research
Type 2 diabetes disproportionately affects older adults, persons from racial and ethnic minority groups, and persons of low socioeconomic status. It can be prevented or delayed through evidence-based interventions such as the National Diabetes Prevention
Boon Peng Ng   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

ChatGPT translation vs. human translation: an examination of a literary text

open access: yesCogent Social Sciences
This study evaluates the proficiency of ChatGPT-based translation compared to Human Translation (HT) using an Arabic literary work. It also examines potential translation gaps in ChatGPT and explores its potential to replace human translators.
Rafat Al Rousan   +2 more
doaj   +1 more source

Hand in hand: automatic sign Language to English translation [PDF]

open access: yes, 2007
In this paper, we describe the first data-driven automatic sign-language-to- speech translation system. While both sign language (SL) recognition and translation techniques exist, both use an intermediate notation system not directly intelligible for ...
Dreuw, Philippe   +4 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Translating Subtitles - Translating Cultures

open access: yesJournal of Siberian Federal University. Humanities & Social Sciences, 2015
The paper focuses upon the problem of trans-cultural transfer in subtitling as a type of audiovisual translation. The methodology of the research involves analysis of the key procedures used for translating culture-specific concepts taking into consideration the principles of dynamic equivalence and the restrictions, applied to the text and the ...
openaire   +2 more sources

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