Results 41 to 50 of about 49,648 (260)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Competences in Translation and Interpreting
Studies About Languages, 2012 This paper examines competences in translation and interpreting that students have to acquire in University studies and need for translator’s or interpreter’s jobs in the European Union (EU) institutions. The research is based on the analysis of responses obtained independently by two questioners. The survey was designed in accordance with the European
Ligija Kaminskienė +1 more
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Ibérica, 2019 The main purpose of the Ba in Translation and Interpreting is, or should be, the acquisition of “translation competence”. This concept has been particularly significant in the field of Translation Teaching, which has been the object of many studies ...
Julia Lobato Patricio
doaj
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
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Acquisition of translation competence and translation acceptability: An experimental study
Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2015 The PhD research project presented in this paper is part of the large-scale experimental research project carried out by PACTE group on the acquisition of translation competence (ATC).
Luis Miguel Castillo Rincón
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
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TRAINING TRANSLATORS: FROM GENERAL REQUIREMENTS TO PARTICULAR APPROACHES
Novìtnâ Osvìta, 2017 This article deals with some aspects of teaching translation. This question has not received much attention not only in Ukraine, but in Translation Studies as a whole.
Nataliya Sopylyuk
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Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
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