Results 31 to 40 of about 1,441,243 (240)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Giving up or Pursuing Translation? The Impact of Strategic Competence on Motivational Persistence
Selçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2020 This study aims to analyse the strategic competence that Translation Studies students develop during the translator training process according to some variables and to explore its impact on the pursuit of translation goals.
Ayşe Işık Akdağ
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
SMART LEARNING MODELS OF CERTIFIED LEGAL TRANSLATORS AND INTERPRETERS
Comparative Legilinguistics, 2019 Legal translation has played an important part in the contact between different people and countries in the history, and is playing an even more significant role in the increasingly globalized world nowadays. The paper is to explore smart learning models
Ming XU
doaj +4 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Educazione Linguistica Language Education, 2020 In everyday communication, both in specialized and non-specialized contexts, translation plays a pivotal role. Although it was considered an outsider in language teaching for decades, translation has now been rehabilitated and should now be considered
Pergola, Ruggiero
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
An evaluation of the EMT: Compatibility with the professional translator’s needs
Cogent Arts & Humanities, 2019 Appeal towards training translators as a sector in translation studies has had a dramatic increase throughout the past decade due to the needs for intercultural communication.
Mohammad Reza Esfandiari +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Borrowers: Researching the cognitive aspects of translation [PDF]
, 2013 The paper considers the interdisciplinary interaction of research on the cognitive aspects of translation. Examples of influence from linguistics, psychology, neuroscience, cognitive science, reading and writing research and language technology are given,
O'Brien, Sharon +2 more
core +2 more sources