Results 51 to 60 of about 1,034,090 (297)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Kansas Department of Corrections News Release

open access: yes, 2012
Gov. Brownback Signs Bill Establishing Justice Reinvestment Team Working Group to Reduce Corrections Costs, Improve Public Safety -- Hutchinson, Kan., Correctional Facility Honored for Reducing Waste -- Jeremy Barclay Named as Communications Director for
Kansas. Department of Corrections.
core   +1 more source

A reduced inner product for kink states

open access: yesJournal of High Energy Physics, 2023
Solitons in classical field theories correspond to states in quantum field theories. If the spatial dimension is infinite, then momentum eigenstates are not normalizable.
Jarah Evslin, Hui Liu
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Correcting Length Bias in Neural Machine Translation [PDF]

open access: yesProceedings of the Third Conference on Machine Translation: Research Papers, 2018
We study two problems in neural machine translation (NMT). First, in beam search, whereas a wider beam should in principle help translation, it often hurts NMT. Second, NMT has a tendency to produce translations that are too short. Here, we argue that these problems are closely related and both rooted in label bias.
Kenton Murray, David Chiang 0001
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Die Übersetzung des Genfer Katechismus (1542/1545) ins Deutsche durch Zacharias Ursinus im Jahr 1563

open access: yesKoers : Bulletin for Christian Scholarship, 2009
The translation of the Genevan Catechism (1542/1545) into German by Zacharias Ursinus in 1563 It is with considerable surprise that one finds in the “Opera Selecta Calvini” vol. 2 a German translation of Calvin’s Geneva Catechism (1542/1545).
W.H. Neuser
doaj   +1 more source

Grammatical Error Correction: Machine Translation and Classifiers [PDF]

open access: yesProceedings of the 54th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers), 2016
We focus on two leading state-of-the-art approaches to grammatical error correction – machine learning classification and machine translation. Based on the comparative study of the two learning frameworks and through error analysis of the output of the state-of-the-art systems, we identify key strengths and weaknesses of each of these approaches and ...
Alla Rozovskaya, Dan Roth 0001
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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