Results 141 to 150 of about 4,831,098 (338)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Translation Errors on Public Place Signboards: An Error Analysis and Translation Strategies Applied [PDF]

Seminar Nasional Struktural 2018, 2018
Translation has been used by people for centuries. Translation is now used in so many aspects, such as economy, business, technology, and health. Translation is changing a meaning from one language to another language. The purpose of translation is to convey the original tone and intent of a message, taking into account cultural and regional ...
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

THE SIGNIFICANCE OF ERRORS IN TRANSLATION DIDACTICS [PDF]

This article aims to shed light on the importance of errors in the field of translation didactics, since it has been widely recognized as an efficacious pedagogical instrument for teaching translation. In this context, we will emphasize the significance
Hamlili ISMAIL
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

An analysis of the role of micro and macro levels in rendering some standard Arabic proverbs into English [PDF]

, 2013
This thesis was inspired by my MA Dissertation back in (2007). This dissertation dealt with 'situationality'. After a couple of years, there was a need to explore other aspects of translation.
Othman, Othman Ahmed Omran
core  

Error analysis of translation outputs of the Siswati-English Linguistic Translation Tool

Cogent Arts & Humanities
The development of machine translation (MT) systems for low-resourced languages in South Africa, such as Siswati, is crucial for bridging the linguistic divide between speakers of this language and English.
Muzi Matfunjwa, Respect Mlambo
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

COMPUTER-ASSISTED TRANSLATION RISKS AND THREATS IN LEGAL TEXTS [PDF]

Strategii Manageriale, 2014
In a world in which IT is developing faster than ever, providing reliable solutions to all problems, regardless the field of interest, the issue of computer-assisted translation systems is more and more complex, offering both advantages and disadvantages.
Georgiana, MÎNDRECI
doaj