Results 121 to 130 of about 758,312 (301)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

COMPUTER-ASSISTED TRANSLATION RISKS AND THREATS IN LEGAL TEXTS [PDF]

open access: yesStrategii Manageriale, 2014
In a world in which IT is developing faster than ever, providing reliable solutions to all problems, regardless the field of interest, the issue of computer-assisted translation systems is more and more complex, offering both advantages and disadvantages.
Georgiana, MÎNDRECI
doaj  

An analysis of machine translation errors on the effectiveness of an Arabic-English QA system [PDF]

open access: yes, 2006
The aim of this paper is to investigate how much the effectiveness of a Question Answering (QA) system was affected by the performance of Machine Translation (MT) based question translation.
Al-Maskari, A., Sanderson, M.
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

ERRORS AND DIFFICULTIES IN TRANSLATING LEGAL TEXTS [PDF]

open access: yesStrategii Manageriale, 2014
Nowadays the accurate translation of legal texts has become highly important as the mistranslation of a passage in a contract, for example, could lead to lawsuits and loss of money.
Camelia, CHIRILA
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

The polylogue project: part 2: errors: lots in translation [PDF]

open access: yes, 2012
This collective piece [edited by F. Senn, E. Mihalycsa and J. Wawrzycka], the work of nine authors and covering some ten languages, examines the creative possibilities of translation to invent analogous forms to the broad range of (volitional) errors ...
Bindervoet, Erik   +8 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Errores y problemas de la traducción literaria en "Makar Chudrá" [PDF]

open access: yes, 2018
[ES] El presente Trabajo de Fin de Grado se centra en el análisis de los errores, problemas y dificultades de la traducción literaria, concretamente en una traducción en castellano (Otero, 2011, Alba Editorial) y una traducción en inglés (Wettlin, 1978 ...
Zubiri Stevens, Savannah
core  

Home - About - Disclaimer - Privacy