Results 51 to 60 of about 617,923 (306)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Translation as an entrepreneurship and an Effective Factor in Small Businesses Growth: Evidence from the Field of Saudi Translation

مجلة العلوم التربوية والدراسات الإنسانية سلسلة الآداب والعلوم التربوية والإنسانية والتطبيقية
This study focuses on the importance of translation as a growing industry sector in Saudi society. It aims at investigating the reality of translation sector as an entrepreneurship, and the role of AI in translation in Saudi Arabia. Using the descriptive
Elghali Mahmoud Seddaig
doaj   +1 more source

Soviet industry and the Red Army under Stalin : a military-industrial complex? [PDF]

, 2001
The paper considers some of the views of the Stalin–era relationship between Soviet industry and the Red Army that are current in the literature, and disentangles some confusions of translation.
Harrison, Mark
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The impact of an industry-driven translation training program on the performance of trainee translators

Cogent Arts & Humanities
This study reports on a quasi-experimental study on the effect of an industry-driven online translation training program on the translator trainees’ performance across five indicators: language, accuracy, terminology, style and clarity.
Buthainah M. Al Thowaini, Mutahar Qassem
doaj   +1 more source

industrial process for quality machine translation

The Journal of Specialised Translation, 2013
Machine translation (MT) is not a tool. Machine translation is an industrial process. Selecting the right MT engine – rules-based (RBMT), statistical (SMT) or hybrid – is just one part of a process that, if correctly managed, is capable of lowering translation costs, increasing productivity and even improving quality and consistency. To reach this goal,
openaire   +2 more sources

Bible Localization and the Politics of Memory and Oblivion [PDF]

, 2011
For centuries the Bible and its teaching have been used to construct identities in the Western world. Today the range of ‘legitimate’ identities is much larger than several decades ago.
Naimushin, Boris
core  

MLPerf Inference Benchmark

, 2020
Machine-learning (ML) hardware and software system demand is burgeoning. Driven by ML applications, the number of different ML inference systems has exploded.
Anderson, Brian, Breughe, Maximilien, Charlebois, Mark, Cheng, Christine, Chou, William, Chukka, Ramesh, Coleman, Cody, Davis, Sam, Deng, Pan, Diamos, Greg, Duke, Jared, Fick, Dave, Gardner, J. Scott, Hubara, Itay, Idgunji, Sachin, Jablin, Thomas B., Jiao, Jeff, John, Tom St., Kanter, David, Kanwar, Pankaj, Lee, David, Liao, Jeffery, Lokhmotov, Anton, Massa, Francisco, Mattson, Peter, Meng, Peng, Micikevicius, Paulius, Osborne, Colin, Pekhimenko, Gennady, Rajan, Arun Tejusve Raghunath, Reddi, Vijay Janapa, Schmuelling, Guenther, Sequeira, Dilip, Sirasao, Ashish, Sun, Fei, Tang, Hanlin, Thomson, Michael, Wei, Frank, Wu, Carole-Jean, Wu, Ephrem, Xu, Lingjie, Yamada, Koichi, Yu, Bing, Yuan, George, Zhang, Peizhao, Zhong, Aaron, Zhou, Yuchen   +46 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Recent trends in the translation industry in Slovenia

JoSTrans: The Journal of Specialised Translation, 2008
Following two earlier studies, which examined the use of translation tools and the needs of the translation job market, this paper reports on the results of an empirical study into the state of affairs in the Slovene translation industry. A survey of the
Darja Fišer
doaj   +1 more source