Results 21 to 30 of about 1,545,528 (302)

Promotion of Viral IRES-Mediated Translation Initiation under Mild Hypothermia. [PDF]

PLoS ONE, 2015
Internal ribosome entry site (IRES)-mediated translation is an essential replication step for certain viruses. As IRES-mediated translation is regulated differently from cap-dependent translation under various cellular conditions, we sought to ...
Maria Licursi, Ricardo A Carmona-Martinez, Seyd Razavi, Kensuke Hirasawa   +3 more
doaj   +1 more source

Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

Cell Reports, 2019
Summary: Sequences within 5′ UTRs dictate the site and efficiency of translation initiation. In this study, an unbiased screen designed to interrogate the 5′ UTR-mediated regulation of the growth-promoting gene MYC unexpectedly revealed the ribosomal ...
Hema Manjunath, He Zhang, Frederick Rehfeld, Jaeil Han, Tsung-Cheng Chang, Joshua T. Mendell   +5 more
doaj   +1 more source

Eukaryotic translation initiation factors and cancer

Tumor Biology, 2017
Recent technological advancements have shown tremendous mechanistic accomplishments in our understanding of the mechanism of messenger RNA translation in eukaryotic cells.
Muhammad Umar Ali, Muhammad Saif Ur Rahman, Zhenyu Jia, Cao Jiang   +3 more
doaj   +1 more source

Mapping codon usage of the translation initiation region in porcine reproductive and respiratory syndrome virus genome

Virology Journal, 2011
Background Porcine reproductive and respitatory syndrome virus (PRRSV) is a recently emerged pathogen and severely affects swine populations worldwide.
Dou Yong-xi, Ma Xu-sheng, Li Ji-dong, He Ya-li, Ma Xiao-xia, Su Jun-hong, Luo Xue-nong, Cai Xue-peng   +7 more
doaj   +1 more source

Reversal of G-Quadruplexes’ Role in Translation Control When Present in the Context of an IRES

Biomolecules, 2022
G-quadruplexes (GQs) are secondary nucleic acid structures that play regulatory roles in various cellular processes. G-quadruplex-forming sequences present within the 5′ UTR of mRNAs can function not only as repressors of translation but also as elements
Mohammed Enamul Hoque, Thulasi Mahendran, Soumitra Basu   +2 more
doaj   +1 more source

Translation initiation factor eIF3 promotes programmed stop codon readthrough. [PDF]

, 2015
Programmed stop codon readthrough is a post-transcription regulatory mechanism specifically increasing proteome diversity by creating a pool of C-terminally extended proteins.
von der Haar, Tobias, Beznoskova, Petra, Wagner, Susan, Valasek, Leos S, Jansen, Myrte E   +4 more
core   +1 more source

Translation Policies in Legal and Institutional Settings [PDF]

, 2021
This edited volume documents the state of the art in research on translation policies in legal and institutional settings. Offering case studies of past and present translation policies from several parts of the world, it allows for a compelling ...

core   +1 more source

A Comprehensive, Quantitative, and Genome-Wide Model of Translation [PDF]

, 2010
Translation is still poorly characterised at the level of individual proteins and its role in regulation of gene expression has been constantly underestimated.
Piotr Zielenkiewicz, Siwiak, Marlena, Marlena Siwiak, Zielenkiewicz, Piotr   +3 more
core   +1 more source

Experimental characterization of Cis-acting elements important for translation and transcription in Halophilic Archaea [PDF]

, 2007
Summary The basal transcription apparatus of archaea is well characterized. However, much less is known about the mechanisms of transcription termination and translation initation.
Jörg Soppa, Oliver Hering, Brenneis, Mariam, Mariam Brenneis, Soppa, Jörg (Prof. Dr.), Brenneis Mariam, Hering, Oliver, Lange, Christian, Christian Lange, Hering Oliver, Soppa Jörg, Lange Christian   +11 more
core   +2 more sources

Regulation of Leaderless mRNA Translation in Bacteria

Microorganisms, 2022
In bacteria, the translation of genetic information can begin through at least three different mechanisms: canonical or Shine-Dalgarno-led initiation, readthrough or 70S scanning initiation, or leaderless initiation.
Lorenzo Eugenio Leiva, Assaf Katz
doaj   +1 more source